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SAVE THE DATE
"Cell Death in Development and Disease"
June 18-21, 2017
Weizmann Institute, Rehovot, Israel.
 

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Tentative Program Cork

Conference location:The Kingsley Hotel, Victoria Cross, Cork, Ireland

“Cell Death and its Translational Ramification”

Conference location:The Kingsley Hotel, Victoria Cross, Cork, Ireland

DATE: June 2-June 4, 2016

Organizers:

Tom Cotter, R.A. Lockshin, Z. Zakeri

Registration opens at 9 AM-6PM

WORKSHOP ON CELL DEATH Methods:

This workshop is free of charge to all students

Thursday June 2nd

Chair:Katharina D'Herde, (Belgium):

1:00-1:30         Mauro Piacentini, (Italy): Regulation of proteostasis under stressful cellular conditions

1:30-2:00         Devrim Gozuacik, (Turkey):  Value of Micro RNAs in cell death

2:00- 2:30        Samuel Katz, (U.S.A): Mitochondrial control of apoptosis

2:30-3:00         Jerry Chipuk, (USA): The BCL-2 Family:  From Basic Apoptosis to the Clinic and Beyond

***************************************************************************************************************

OFFICIAL START OF THE SCIENTIFIC SESSIONS OF THE MEETING

Thursday June 2nd

Welcome Introduction and awards:

Chair: Zahra Zakeri, (USA): 

4:15-4:30         Zahra Zakeri, (U.S.A):  Introduction and welcome:

4:30-4:45         Richard A. Lockshin, (U.S.A): Presenting Award to Hermann Steller

4:45-5:30         Hermann Steller (USA): Regulation of apoptosis in development, stem cells and cancer

5:30-5:45         Tom Cotter (Ireland): Presenting Award to Seamus Martin

5:45-6:30         Seamus Martin (Ireland): Cell Death: An Inflammatory Perspective'

7:00-                Dinner  

Friday  June 3rd 

Cell Death and Cancer Therapy: 

Chair:Annie Joubert, (South Africa):

Boris Zhivotovsky, (Sweden): miRNAs' role in sensitivity of lung adenocarcinoma to treatment

Marc Diederich, (Republic of Korea): Cardenolides trigger mitophagy, apoptosis or necroptsis in human neuroblastoma

Erik Norberg, (Sweden): Profiling and targeting of tumor metabolism

Chair: Dhyan Chandra, (USA): 

Simone Fulda, (Germany):Novel opportunities for exploiting programmed cell death pathways for cancer therapy

Rolf Brekken, (USA): Blockade of phosphatidylserine and immune activation in cancer’

Adrienne Gorman, (Ireland): Targeting cell survival pathways in breast cancer

Lunch and “Technical workshop: information provided by companies”

Mechanisms of Cell Death Mitochondria: 

Chair: Jerry Chipuk,  (U.S.A):

Sarit Larisch, (Israel): ARTS initiates apoptosis by regulating XIAP and Bcl-2 family members

Triona Ni Chonghaile, (Ireland):Determining mitochondria's distance to death's door

Chair:Marianne Cronjé (South Africa)

Atan Gross (Israel):Importance of mitochondria metabolism for regulating the DNA damage response in hematopoietic stem cells

Johannes V. Swinnen, (Belgium): Regulation of cell death susceptibility by modulating mitochondrial phospholipid saturation

Poster Viewing

Saturday June 4th

Mechanisms of Cell Death and host defense: 

Chair: Marie-Lise Gougeon, France:

Helin Norberg, (Sweden): CMA, Metabolic catastrophe and cell death

Benedicte Py. (France): Regulation of the NLRP3 inflammasome by post-translational modifications

Zvi Fishelson, (Israel): Activators and inhibitors of programmed necrotic cell death induced by the complement C5b-9 complex 

Mechanisms of Cell Death--Caspases and other mechanisms

Chair: Carlos Penaloza (U.S.A): 

Marcos A. Carpio: (U.S.A): Regulation of apoptosis by pro-apoptotic BOK

Eli Arama (Israel): Move or Die: Linking caspases and cell migration and invasion in Drosophila

Muñoz Pinedo Cristina (Spain):Caspase-8 dependent apoptosis induced by glucose deprivation

Mechanisms of Cell Death Role of ROS:

Chair: Samuel Katz (U.S.A): 

Tom Cotter (Ireland):Redox signalling in tumour cell survival

Frank Böhmer (Germany) :Redox regulation of FLT3ITD signaling in cells of Acute Myeloid Leukemia

Mechanisms of Cell Death Role of ROS:

Chair: Raymond Birge; (U.S.A):

Alex Tonks (UK): The role of reactive oxygen species in acute myeloid leukaemia; cell death, proliferation and metabolism

Shazib Pervaiz (Singapore):The protective effect of S70 phosphorylated Bcl-2 against DNA damage induced by SOD1 downregulation in cancer cells.

5:00-7:00         WORKSHOP ON BUILDING A CAREER IN THE FIELD OF CELLDEATH: WHAT IS THE FUTURE OF THIS FIELD?: PANEL DISCUSSION.

Chair:              Zahra Zakeri

 Panelists; : Samuel Katz; Katharina D'Herde;Eli Arama; Sarit Larisch, Jerry Chipuk; Simone Fulda; Seamus Martin

8:30                 Gala Dinner

Meeting Prizes 2016

PRESENTATION PRIZES SPONSORED BY TRADE (Thanks to the generosity of our sponsors: Science Foundation Ireland; Peregrine Pharmaceuticals; Queens College of the City University of New York; Biosciences Ltd; Anachem Ltd; Brennan & Co., Ltd)

Selected oral presentation prize:      

Alice Wyse Jackson-(University College Cork, Ireland), PHOTORECEPTOR-MICROGLIAL CROSSTALK IN THE DEGENERATING RETINA: FRACKTALKINE-CX3CR1 SIGNALLING, Wyse Jackson AC, Roche SL, Cotter TG, Cell Death and Disease Laboratory, Biosciences Institute, University College Cork, Ireland

Poster prizes (No order intended):

  1. Monica Vara- Perez- Poster prize winner (KU Leuven, Belgium) ,BNIP3 SUPPORTS MELANOMA AGGRESSIVENESS BY INHIBITING THE PROLYL HYDROXYLASES TARGETING HIF1A FOR DEGRADATION VIA ALTERED OUTPUT OF MITOCHONDRIAL METABOLITES, Hannelore MAES 1, Monica VARA-PEREZ1, Sarah VAN DINGENEN1, Alex VAN VLIET1, Patrizia AGOSTINIS1,1. Lab of Cell Death Research and Therapy, Department of Cellular and Molecular Medicine, Campus Gasthuisberg, KU Leuven, Belgium
  2. Sebastian Bittner- Poster Prize Winner (University Hospital of Regensburg, Germany) MOLECULAR MECHANISMS OF DEATH RECEPTOR 3 SIGNALING. Sebastian Bittner, Martin Ehrenschwender, Institute of Clinical Microbiology and Hygiene; University Hospital of Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany
  3. Anna Gorelick Ashkenazi- Poster Prize Winner (Weizmann Institute, Israel) LINKING CASPASES AND CELL MIGRATION AND INVASION IN DROSOPHILA. Gorelick-Ashkenazi A, Weiss R, Florentin A, Dweik D, Arama E. Weizmann Institute of Science, Israel
  4. Joselyn Landazuri Vinueza-Poster Prize Winner (Queens College of CUNY, USA) DIFFERENT SEROTYPES OF DENGUE PERSISTENTLY INFECT MAMMALIAN KIDNEY CELLS AND USE THE NS4A PROTEIN TO UPREGULATE AUTOPHAGY THROUGH AN ATM KINASE-DEPENDENT PATHWAY Landazuri Vinueza, S Ghosh Roy, N Zali, E Datan , A Ramnauth, R A Lockshin, and Z Zakeri, Department of Biology, Queens College and Graduate Center of the CUNY

Travel fellowship (Richard A Lockshin support for students):

Ishmael Obaidi, SBBS, Ireland, CURCUMIN SENSITIZES RENAL CARCINOMA CELLS TO TRAIL INDUCED APOPTOSIS, Obaidi I, and McMorrow T. Renal Disease Research Group, UCD School of Biomolecular and Biomedical Science, Conway Institute, University College Dublin,

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