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This page offers access to items offered by the society to raise money for scholarships, as well as links to other sites of interest. SUGGESTIONS FOR SITES OF INTEREST SHOULD BE ADDRESSED TO THE WEBMASTER. Mouse over the button and choose books or clothing commemorative of our 20th anniversary.

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Commemorative Material

ICDS 20th Anniversary 2014

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T-SHIRT
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Crew-neck 
BASEBALL CAP
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Not stamped! 
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photo 2 photo 2 photo 5

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Books For Sale

 20 Years of Cell Death  Born This Way I & II

 

20 Years of Cell Death

Cover800

AVAILABLE FROM ALL PROMINENT BOOKSELLERS

Ebook: $20; Print on Demand: $40

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(Just Out!)

20 Years of Cell Death

An Anniversary Publication of ICDS

Beginning in 1990, research into apoptosis and programmed cell death expanded exponentially, as biomedical scientists recognized that most cells do not die accidentally, the commit suicide under specific conditions. This death is highly controlled, and several discoveries during that period confirmed that the timing and extent of cell death determined the normal development of embryos as well as whether adults lived healthy, balanced lives or whether they developed cancers, Alzheimer's or other neurodegenerative diseases, or lupus or autoimmune disease.

This work recounts what we have learned in the last twenty years and where current research is taking us. In seventeen chapters written by founders and current leaders in the field, the discoveries and growth of ideas are explored, often from a personal and always highly readable basis, so that the book provides a solid background for senior and junior researchers as well as those trying to grasp its importance and those interested in how scientific fields are born and how they grow. The various chapters trace the simpler ideas with which we started and how they grew more complex. The first part of the book addresses current understanding of the mechanisms by which cells self-destruct through apoptosis.and raises the question of what other roles the components of apoptosis play in healthy cells. In the second part, the authors look at the larger picture of apoptosis as a physiological process, under positive and negative control and determining the balance between cell birth and death. In Part 3, top researchers explore alternatives to apoptosis, such as autophagy and necroptosis. Finally, in part 4, the authors examine the impact of control of cell death in determining the outcome of disease states such as viral infection and cancer.

Over the past twenty years we have come to understand the mechanics and components of programmed cell deaths. For true clinical efficacy, we need to understand how the threshold is established at which cells commit to suicide, the extent to which their history and current metabolism changes that threshold, and why seemingly similar cells respond differently. Several of the authors address these questions and point to the directions of future research.

The International Cell Death Society has sponsored this work on the occasion of its 20th anniversary. By issuing it as an e-book and print on demand, it lowers the cost of this resource to a level where students, senior scientists, and scholars can find it within reach.

Table of Contents

Dedication and Acknowledgment

Chapter 1: Introduction (Lockshin and Zakeri)

Part 1. COMPONENTS AND PATHWAYS OF APOPTOSIS

Chapter 2: Endoplasmic Reticulum stress in Cancer and Cell Death: a time lapse (Agostinis)

Chapter 3: c-FLIP: A negative regulator of programmed cell death and a target for cancer therapy (Pennarun, Bucor, and Khosravi-Far)

Chapter 4: Transglutaminase Type2 and Cell Death: an historical overview. (Piacentini)

Chapter 5: Caspases: helpers and killers (Zhivotovsky)

Chapter 6: Seeking day jobs for all apoptosis-related factors – inside one perspective (Hardwick)

PART 2--PROCESSES OF APOPTOSIS

Chapter 7: Modern history of the study of cell death: 1964...1994...2014 (Zakeri and Lockshin)

Chapter 8: Efferocytosis: Molecular Mechanisms and Immune Signaling from Dying Cells (Kumar, Smith, and Birge)

Chapter 9: From caterpillars to clinic: IAP proteins and their antagonists (Vucic)

Chapter 10: How do cells stay alive? (Green, Llambi, and Fienberg)

PART 3: AUTOPHAGY AND NECROPTOSIS

Chapter 11. Apoptosis and Autophagy face to face: Apaf1 and Ambra1 as a paradigm (De Zio and Cecconi)

Chapter 12. Cell Death and Autophagy: A Historical Perspective (Gozuacik and Kig)

Chapter 13: Autophagic flux and cell death (Loos)

Chapter 14: Discovery of key mechanisms of cell death: from apoptosis to necroptosis (Yuan)

PART 4: VIRUSES AND CANCER

Chapter 15: Cell death and virus infection – a short review (Zakeri et al)

Chapter 16: Harnessing apoptosis pathways for childhood cancer (Fulda)

Chapter 17: South African medicinal plants inducing apoptosis in cancer cells: a treasure trove of anti-cancer agents? (van der Walt and Cronjé)

Choose which volume, and electronic or print version, in the drop-down panel below. IF YOU ARE A MEMBER OF ICDS, you may write "Member" in the coupon box on a following page and receive a 33% discount. No tax is charged.

$0.00
* Books:

Quantity:



 

Born This Way Volumes I and II

 

SmallCover1

smallcover2 

 

A senior and well-published scientist describes, through anecdotes, parables, and stories how scientists conceive, ask, and answer questions, and how what they do develops from the culture of their time. Part 1 describes the origins of modern biological science. It addresses issues such as why the story of evolution arose in the 19th C, and not before or after, how the evidence was gathered, and how its misuse led to some terrible decisions by societies. Part 2 describes the rules for experimental science, what constitutes a good versus a poor experiment, how hypotheses, such as the hypothesis or the origin of AIDS, are tested and evaluated. The author goes on to describe the origins of molecular biology and the "cool tricks" that created a billionfold greater ability to analyze living things, leading to the miraculous capabilities that we have today.Part 1 describes the origins of modern biological science. It addresses issues such as why the story of evolution arose in the 19th C, and not before or after, how the evidence was gathered, and how its misuse led to some terrible decisions by societies. Part 2 describes the rules for experimental science, what constitutes a good versus a poor experiment, how hypotheses, such as the hypothesis or the origin of AIDS, are tested and evaluated. The author goes on to describe the origins of molecular biology and the "cool tricks" that created a billionfold greater ability to analyze living things, leading to the miraculous capabilities that we have today.

 

Born This Way, Volumes 1 and 2, print and electonic

===========

 Choose which volume, and electronic or print version, in the drop-down panel below. IF YOU ARE A MEMBER OF ICDS, you may write "Member" in the  coupon box on a following page and receive a 33% discount. No tax is charged.

$0.00
* Books:

Quantity:


 .viewcart2W

View in a new window without leaving this page. The transient "View Cart" button that appears below when you choose "Add to Cart" will take you from this page. In that case, use the back button to return. Members will receive a 33% discount. PayPal button will permit payment either through PayPal or through Credit Card.


 

 

$0.00
* Books:

Quantity:

Clothing (2)

 

Commemorative Material

ICDS 20th Anniversary 2014

Available while supplies last

 

T-shirt
Women's
V-neck

T-shirt
Men's,
Crew-neck

Baseball cap
Logo is stitched,
Not stamped!

 photo 1  photo 3 photo 4
 photo 2  photo 2 photo 5

 


button ViewCart

View in a new window without leaving this page. The transient "View Cart" button that appears below when you choose "Add to Cart" will take you from this page. In that case, use the back button to return. 


Members will receive a 33% discount (coupon code: "member"). PayPal button will permit payment either through PayPal or through Credit Card.

$15.00
Quantity:

Born This Way (2)

 

 

Just Out!

20 Years of Cell Death

An Anniversary Publication of ICDS

 Cover800

 

AVAILABLE FROM ALL PROMINENT BOOKSELLERS

e-Book: $20

Print On Demand: $40

Beginning in 1990, research into apoptosis and programmed cell death expanded exponentially, as biomedical scientists recognized that most cells do not die accidentally, the commit suicide under specific conditions. This death is highly controlled, and several discoveries during that period confirmed that the timing and extent of cell death determined the normal development of embryos as well as whether adults lived healthy, balanced lives or whether they developed cancers, Alzheimer's or other neurodegenerative diseases, or lupus or autoimmune disease. 

This work recounts what we have learned in the last twenty years and where current research is taking us. In seventeen chapters written by founders and current leaders in the field, the discoveries and growth of ideas are explored, often from a personal and always highly readable basis, so that the book provides a solid background for senior and junior researchers as well as those trying to grasp its importance and those interested in how scientific fields are born and how they grow. The various chapters trace the simpler ideas with which we started and how they grew more complex. 

The first part of the book addresses current understanding of the mechanisms by which cells self-destruct through apoptosis.and raises the question of what other roles the components of apoptosis play in healthy cells. In the second part, the authors look at the larger picture of apoptosis as a physiological process, under positive and negative control and determining the balance between cell birth and death. In Part 3, top researchers explore alternatives to apoptosis, such as autophagy and necroptosis. Finally, in part 4, the authors examine the impact of control of cell death in determining the outcome of disease states such as viral infection and cancer.

Over the past twenty years we have come to understand the mechanics and components of programmed cell deaths. For true clinical efficacy, we need to understand how the threshold is established at which cells commit to suicide, the extent to which their history and current metabolism changes that threshold, and why seemingly similar cells respond differently. Several of the authors address these questions and point to the directions of future research. 

The International Cell Death Society has sponsored this work on the occasion of its 20th anniversary. By issuing it as an e-book and print on demand, it lowers the cost of this resource to a level where students, senior scientists, and scholars can find it within reach.

 


 Table of Contents

Dedication and Acknowledgment

Chapter 1: Introduction (Lockshin and Zakeri)

Part 1. COMPONENTS AND PATHWAYS OF APOPTOSIS

Chapter 2: Endoplasmic Reticulum stress in Cancer and Cell Death: a time lapse (Agostinis)

Chapter 3: c-FLIP: A negative regulator of programmed cell death and a target for cancer therapy (Pennarun, Bucor, and Khosravi-Far)

Chapter 4: Transglutaminase Type2 and Cell Death: an historical overview. (Piacentini)

Chapter 5: Caspases: helpers and killers (Zhivotovsky)

Chapter 6: Seeking day jobs for all apoptosis-related factors – inside one perspective (Hardwick)

PART 2--PROCESSES OF APOPTOSIS

Chapter 7: Modern history of the study of cell death: 1964...1994...2014 (Zakeri and Lockshin)

Chapter 8: Efferocytosis: Molecular Mechanisms and Immune Signaling from Dying Cells (Kumar, Smith, and Birge)

Chapter 9: From caterpillars to clinic: IAP proteins and their antagonists (Vucic)

Chapter 10: How do cells stay alive? (Green, Llambi, and Fienberg)

PART 3: AUTOPHAGY AND NECROPTOSIS

Chapter 11. Apoptosis and Autophagy face to face: Apaf1 and Ambra1 as a paradigm (De Zio and Cecconi)

Chapter 12. Cell Death and Autophagy: A Historical Perspective (Gozuacik and Kig)

Chapter 13: Autophagic flux and cell death (Loos)

Chapter 14: Discovery of key mechanisms of cell death: from apoptosis to necroptosis (Yuan)

PART 4: VIRUSES AND CANCER

Chapter 15: Cell death and virus infection – a short review (Zakeri et al)

Chapter 16: Harnessing apoptosis pathways for childhood cancer (Fulda)

Chapter 17: South African medicinal plants inducing apoptosis in cancer cells: a treasure trove of anti-cancer agents? (van der Walt and Cronjé)

 


 

smallCovers1and2

Born This Way, Volumes 1 and 2, print and electonic


Choose which volume, and electronic or print version, in the drop-down panel below.

IF YOU ARE A MEMBER OF ICDS, you may write "Member" in the  coupon box on a following page and receive a 33% discount. No tax is charged.


 .button ViewCart

View in a new window without leaving this page. The transient "View Cart" button that appears below when you choose "Add to Cart" will take you from this page. In that case, use the back button to return. Members will receive a 33% discount. PayPal button will permit payment either through PayPal or through Credit Card.


 

 

$10.00
Quantity:

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