Tentative Program Cork

Conference location:The Kingsley Hotel, Victoria Cross, Cork, Ireland

“Cell Death and its Translational Ramification”

Conference location:The Kingsley Hotel, Victoria Cross, Cork, Ireland

DATE: June 2-June 4, 2016

Organizers:

Tom Cotter, R.A. Lockshin, Z. Zakeri

Registration opens at 9 AM-6PM

WORKSHOP ON CELL DEATH Methods:

This workshop is free of charge to all students

Thursday June 2nd

Chair:Katharina D'Herde, (Belgium):

1:00-1:30         Mauro Piacentini, (Italy): Regulation of proteostasis under stressful cellular conditions

1:30-2:00         Devrim Gozuacik, (Turkey):  Value of Micro RNAs in cell death

2:00- 2:30        Samuel Katz, (U.S.A): Mitochondrial control of apoptosis

2:30-3:00         Jerry Chipuk, (USA): The BCL-2 Family:  From Basic Apoptosis to the Clinic and Beyond

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OFFICIAL START OF THE SCIENTIFIC SESSIONS OF THE MEETING

Thursday June 2nd

Welcome Introduction and awards:

Chair: Zahra Zakeri, (USA): 

4:15-4:30         Zahra Zakeri, (U.S.A):  Introduction and welcome:

4:30-4:45         Richard A. Lockshin, (U.S.A): Presenting Award to Hermann Steller

4:45-5:30         Hermann Steller (USA): Regulation of apoptosis in development, stem cells and cancer

5:30-5:45         Tom Cotter (Ireland): Presenting Award to Seamus Martin

5:45-6:30         Seamus Martin (Ireland): Cell Death: An Inflammatory Perspective'

7:00-                Dinner  

Friday  June 3rd 

Cell Death and Cancer Therapy: 

Chair:Annie Joubert, (South Africa):

Boris Zhivotovsky, (Sweden): miRNAs' role in sensitivity of lung adenocarcinoma to treatment

Marc Diederich, (Republic of Korea): Cardenolides trigger mitophagy, apoptosis or necroptsis in human neuroblastoma

Erik Norberg, (Sweden): Profiling and targeting of tumor metabolism

Chair: Dhyan Chandra, (USA): 

Simone Fulda, (Germany):Novel opportunities for exploiting programmed cell death pathways for cancer therapy

Rolf Brekken, (USA): Blockade of phosphatidylserine and immune activation in cancer’

Adrienne Gorman, (Ireland): Targeting cell survival pathways in breast cancer

Lunch and “Technical workshop: information provided by companies”

Mechanisms of Cell Death Mitochondria: 

Chair: Jerry Chipuk,  (U.S.A):

Sarit Larisch, (Israel): ARTS initiates apoptosis by regulating XIAP and Bcl-2 family members

Triona Ni Chonghaile, (Ireland):Determining mitochondria's distance to death's door

Chair:Marianne Cronjé (South Africa)

Atan Gross (Israel):Importance of mitochondria metabolism for regulating the DNA damage response in hematopoietic stem cells

Johannes V. Swinnen, (Belgium): Regulation of cell death susceptibility by modulating mitochondrial phospholipid saturation

Poster Viewing

Saturday June 4th

Mechanisms of Cell Death and host defense: 

Chair: Marie-Lise Gougeon, France:

Helin Norberg, (Sweden): CMA, Metabolic catastrophe and cell death

Benedicte Py. (France): Regulation of the NLRP3 inflammasome by post-translational modifications

Zvi Fishelson, (Israel): Activators and inhibitors of programmed necrotic cell death induced by the complement C5b-9 complex 

Mechanisms of Cell Death--Caspases and other mechanisms

Chair: Carlos Penaloza (U.S.A): 

Marcos A. Carpio: (U.S.A): Regulation of apoptosis by pro-apoptotic BOK

Eli Arama (Israel): Move or Die: Linking caspases and cell migration and invasion in Drosophila

Muñoz Pinedo Cristina (Spain):Caspase-8 dependent apoptosis induced by glucose deprivation

Mechanisms of Cell Death Role of ROS:

Chair: Samuel Katz (U.S.A): 

Tom Cotter (Ireland):Redox signalling in tumour cell survival

Frank Böhmer (Germany) :Redox regulation of FLT3ITD signaling in cells of Acute Myeloid Leukemia

Mechanisms of Cell Death Role of ROS:

Chair: Raymond Birge; (U.S.A):

Alex Tonks (UK): The role of reactive oxygen species in acute myeloid leukaemia; cell death, proliferation and metabolism

Shazib Pervaiz (Singapore):The protective effect of S70 phosphorylated Bcl-2 against DNA damage induced by SOD1 downregulation in cancer cells.

5:00-7:00         WORKSHOP ON BUILDING A CAREER IN THE FIELD OF CELLDEATH: WHAT IS THE FUTURE OF THIS FIELD?: PANEL DISCUSSION.

Chair:              Zahra Zakeri

 Panelists; : Samuel Katz; Katharina D'Herde;Eli Arama; Sarit Larisch, Jerry Chipuk; Simone Fulda; Seamus Martin

8:30                 Gala Dinner