Noosa_2002

Schedule as of May 7 2002

Start Time Name Session, Title
     
3:30 PM Z. Zakeri Welcome and Introduction
     
I. Development, Aging, Cell Cycle (Karen Hubbard, Chair)
4:10 PM S. Ucker Molecular dissection of the interface of the cell cycle and cell death
4:45 PM S. Døskeland Cyclin-dependent protein kinase 5 is essential for cAMP-induced apoptosis in a rat leukemia cell line
5:20 L. Lin Short talk: Regulation of Cdk5 in p53-related cell death pathway
5:35 PM S. Lowe Cellular senescence: an alternative to apoptosis in tumor suppression
6:10 PM S. Nagata DNA fragmentation during apoptosis and erythropoiesis
6:45 J. Negrón Short talk: Developmental regulation of apoptosis during zebrafish (Danio rerio) early embryogenesis
     
7:00 PM Social hour and dinner
Saturday June 1, 2002
     
II. What decides the activation of the death process? Death receptors, Extracellular signals and cell-cell interaction (Wilfried Bursch, Chair)
8:30 AM D. Wallach Dynamics of macromolecular complexes in the induction of cell-death by receptors of the TNF/NGF Family
9:05 AM P. Schneider Induction of apoptosis by CARD-containing proteins
9:40 AM S. Martin Novel CARD proteins as regulators of NF-kB activation and apoptosis
10:15 AM C. Troy Short talk: Death in the balance: Regulation of caspase pathways during neuronal death
10:30 AM L. Fésüs Short talk: Neurofibrillary tangles are covalently cross-linked via ubiquitin and HSP 27 by transglutaminases
10:45 AM Coffee  
     
     
III. Intracellular signals 1.  (Sharad Kumar, Chair)
11:15 AM H. Beere Stress induced apoptosis:  Mitochondria, p53, and other detours on the roads to ruin
11:50 AM S. Orrenius Mitochondrial regulation of apoptosis
12:25 PM A. Porter Genes that regulate neuronal differentiation and nitric oxide-induced apoptosis of neuroblastoma cells
1:00 PM S. Szondy Short talk: Tissue transglutaminase is required for phagocytosis of apoptotic cells and to prevent autoimmunity
1:15 PM Lunch  
IV. Intracellular signals 2. (Boris Zhivotovsky, Chair)
2:30 PM J. Yuan Dissecting Cell death pathways by genetic and chemical genetic methods
3:05 PM C. Hawkins Analysis of apoptotic pathways using yeast
3:40PM S. Kornbluth Regulation of apoptotic signaling in a cell-free system
4:15PM Y. Shi Structure-function relationships of caspase-regulating peptides
5:05PM B. Turk Short talk: Lysosomal pathways to apoptosis: role of papain-like cysteine proteases
5:20PM V. Marsden Short talk: APAF-1 and caspase-9 are dispensable for apoptosis of hematopoietic cells
5:35PM Posters  
7:35 Dinner  
     

Sunday June 2

V. Caspases and Execution (Katherina d’Herde, Chair)
8:30 AM D. Nicholson Caspase modus operandi and therapeutic modulation
9:05 AM G. Salvesen Regulation of the execution phase of apoptosis revealed at the molecular level
9:40 AM K. Tomaselli Caspase inhibition as a therapeutic strategy
10:15 AM B. Hay Regulators of apoptosis as measured in the Drosophila eye
10:50 AM S. Mussche Short talk: The extracellular calcium-sensing receptor is linked to a survival pathway in avian granulosa cells
11:05 AM Coffee  
     
VI Cell survival 1.  (Carlos Martínez-A, Chair)
11:35 AM D. Huang Initiation of cell death by the BH3-only proteins
12:10 PM C. Day Structure and biochemistry of Bcl2 homologues
12:50 PM P. Bouillet Short talk: Role of the bh3-only protein bim in autoimmune and degenerative diseases.
1:05 PM L. Dorstyn Short talk: The role of cytochrome c in caspase activation in Drosophila melanogaster cells.
1:20PM Lunch  
     
VII Cell survival 2 (László Fésüs, Chair)
2:20 PM J. Cidlowski Ion channels and the repression of apoptosis
2:55 PM A.Verhagen The role of mammalian IAP antagonists in the regulation of cell death
3:30 PM B. Roth Short talk: Programmed cell death in plants: Identification of plant proteins interacting with the viral Bcl-2 homologue BHRF1
3:45 PM Posters  
7:00 PM Dinner Gala dinner honoring Dr Kerr and presentation of awards

Monday June 3

 

 

 
VIII Engulfment (Ray Birge, Chair)
8:30 AM V. Fadok Regulating phosphatidylserine as a signal
9:05 AM Hengartner Engulfment of apoptotic cells in C elegans
9:40 AM J. Trapani Short talk: Alternative pathways for endocytic uptake of the potently apoptotic lymphocyte serine protease granzyme B.
9:55 AM R. Clem Short talk: Mapping apoptotic pathways using RNAi: DIAP1 promotes cell viability by inhibiting a constitutive death pathway involving DRONC and DARK
10:10 AM K. Ravichandran Short talk: Evolutionarily conserved signaling pathways regulating engulfment of  apoptotic cells
10:25 AM Coffee  
     
IX Translational research: Proteomics, Medicine, and Clinic (Amedeo Columbano, Chair)
10:55 AM P. Brundin Cell death and survival in transplants of embryonic brain tissue used for the treatment of Parkinson’s Disease
11:30 AM A. Haimovitz-Friedman Radiation resistance by targeting apoptosis through activation of ceramide synthase
12:05 PM R. Kitsis Novel approaches to heart attacks and heart failure: Manipulating apoptosis in the myocardium
12:40 PM L. Gustafsson Short talk: HAMLET; a folding variant of human a-lactalbumin that induces apoptosis in tumour cells.
12:55 PM D. Vaux Wrap up
1:15 PM R. Lockshin Closing remarks
1:30 PM   Meeting adjourned