Member Publications

Side-by-side comparison of BH3-mimetics identifies MCL-1 as a key therapeutic target in AML.
Ewald L, Dittmann J, Vogler M, Fulda S
Cell Death Dis 2019 Dec 4
Role of Astrocytes in Post-traumatic Epilepsy.
Xu S, Sun Q, Fan J, Jiang Y, Yang W, et al.
Front Neurol 2019
Loss of Oxidation Resistance 1, OXR1, Is Associated with an Autosomal-Recessive Neurological Disease with Cerebellar Atrophy and Lysosomal Dysfunction.
Wang J, Rousseau J, Kim E, Ehresmann S, Cheng YT, et al.
Am J Hum Genet 2019 Dec 5
Brief Normothermic Machine Perfusion Rejuvenates Discarded Human Kidneys.
Hameed AM, Lu DB, Patrick E, Xu B, Hu M, et al.
Transplant Direct 2019 Nov
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells.
Haydn T, Kehr S, Willmann D, Metzger E, Schüle R, et al.
Int J Cancer 2019 Nov 21
Synergistic Autophagy Effect of miR-212-3p in Zoledronic Acid-Treated In Vitro and Orthotopic In Vivo Models and in Patient-Derived Osteosarcoma Cells.
Oh JY, Kim EH, Lee YJ, Sai S, Lim SH, et al.
Cancers (Basel) 2019 Nov 18
Activity of caspase-8 determines plasticity between cell death pathways.
Newton K, Wickliffe KE, Maltzman A, Dugger DL, Reja R, et al.
Nature 2019 Nov
TRAIL-induced variation of cell signaling states provides nonheritable resistance to apoptosis.
Baskar R, Fienberg HG, Khair Z, Favaro P, Kimmey S, et al.
Life Sci Alliance 2019 Dec
Bypassing pro-survival and resistance mechanisms of autophagy in EGFR-positive lung cancer cells by targeted delivery of 5FU using theranostic Ag<sub>2</sub>S quantum dots.
Duman FD, Akkoc Y, Demirci G, Bavili N, Kiraz A, et al.
J Mater Chem B 2019 Dec 14
AKT1-targeted proapoptotic activity of compound K in human breast cancer cells.
Choi E, Kim E, Kim JH, Yoon K, Kim S, et al.
J Ginseng Res 2019 Oct
ASPP2 inhibits tumor growth by repressing the mevalonate pathway in hepatocellular carcinoma.
Liang B, Chen R, Song S, Wang H, Sun G, et al.
Cell Death Dis 2019 Nov 4
Nanocomposite packaging regulates extracellular ATP and programed cell death in edible mushroom (Flammulina velutipes).
Shi C, Wu Y, Fang D, Ma N, Mariga AM, et al.
Food Chem 2019 Oct 19
Molecular insights on cytochrome c and nucleotide regulation of apoptosome function and its implication in cancer.
Yadav N, Gogada R, O'Malley J, Gundampati RK, Jayanthi S, et al.
Biochim Biophys Acta Mol Cell Res 2020 Jan
A matter of life and death: Molecular, physiological, and environmental regulation of seed longevity.
Zhou W, Chen F, Luo X, Dai Y, Yang Y, et al.
Plant Cell Environ 2019 Nov 1
Correction to: HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy.
Strappazzon F, Di Rita A, Peschiaroli A, Leoncini PP, Locatelli F, et al.
Cell Death Differ 2019 Oct 30
Destined to Die: Apoptosis and Pediatric Cancers.
Choo Z, Loh AHP, Chen ZX
Cancers (Basel) 2019 Oct 23
A TAZ-ANGPTL4-NOX2 Axis Regulates Ferroptotic Cell Death and Chemoresistance in Epithelial Ovarian Cancer.
Yang WH, Huang Z, Wu J, Ding CC, Murphy SK, et al.
Mol Cancer Res 2019 Oct 22
The requirement of SUMO2/3 for SENP2 mediated extraembryonic and embryonic development.
Yu HI, Hsu T, Maruyama EO, Paschen W, Yang W, et al.
Dev Dyn 2019 Oct 17
Involvement of Up-regulation of Death Receptors and Bim in Hispolon-mediated TNF-related Apoptosis-inducing Ligand Sensitization in Human Renal Carcinoma.
Yun JM, Min KJ, Kwon TK
J Cancer Prev 2019 Sep
Effect of novel porphyrazine photosensitizers on normal and tumor brain cells.
Mishchenko TA, Turubanova VD, Mitroshina EV, Alzeibak R, Peskova NN, et al.
J Biophotonics 2019 Oct 8
[Outcome of children with T cell acute lymphoblastic leukemia treated with Chinese Children Leukemia Group acute lymphoblastic leukemia (CCLG-ALL) 2008 protocol].
Liu XM, Chen XJ, Zou Y, Wang SC, Wang M, et al.
Zhonghua Er Ke Za Zhi 2019 Oct 2
Emerging role of mitophagy in cardiovascular physiology and pathology.
Morales PE, Arias-Durán C, Ávalos-Guajardo Y, Aedo G, Verdejo HE, et al.
Mol Aspects Med 2019 Oct 3
Rotenone and 3-bromopyruvate toxicity impacts electrical and structural cardiac remodeling in rats.
Zhan C, Liu G, Li J, Li G, Li T, et al.
Toxicol Lett 2020 Jan
LanCL1 promotes motor neuron survival and extends the lifespan of amyotrophic lateral sclerosis mice.
Tan H, Chen M, Pang D, Xia X, Du C, et al.
Cell Death Differ 2019 Sep 30
Calreticulin is a Critical Cell Survival Factor in Malignant Neoplasms.
Han A, Li C, Zahed T, Wong M, Smith I, et al.
PLoS Biol 2019 Sep
Impaired NF-κB signalling underlies cyclophilin D-mediated mitochondrial permeability transition pore opening in doxorubicin cardiomyopathy.
Dhingra R, Guberman M, Rabinovich-Nikitin I, Gerstein J, Margulets V, et al.
Cardiovasc Res 2019 Sep 6
Single-Cell and Population-Level Analyses Using Real-Time Kinetic Labeling Couples Proliferation and Cell Death Mechanisms.
Gelles JD, Mohammed JN, Santos LC, Legarda D, Ting AT, et al.
Dev Cell 2019 Oct 21
Comparative analysis of urban road dust compositions in relation to their potential human health impacts.
Koh B, Kim EA
Environ Pollut 2019 Dec
Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells.
Pataer A, Ozpolat B, Shao R, Cashman NR, Plotkin SS, et al.
Oncogene 2019 Sep 25
Cellular Stress Responses in Radiotherapy.
Kim W, Lee S, Seo D, Kim D, Kim K, et al.
Cells 2019 Sep 18
The Dark Side of Estrogen Stops Translation to Induce Apoptosis.
Lamb HM, Hardwick JM
Mol Cell 2019 Sep 19
Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites.
Holdgaard SG, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, et al.
Nat Commun 2019 Sep 13
Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis.
Newton K, Wickliffe KE, Dugger DL, Maltzman A, Roose-Girma M, et al.
Nature 2019 Oct
Extracellular vesicles in vascular calcification.
Yang W, Zou B, Hou Y, Yan W, Chen T, et al.
Clin Chim Acta 2019 Dec
Mitochondrial E3 ubiquitin ligase 1 promotes autophagy flux to suppress the development of clear cell renal cell carcinomas.
Yuan Y, Li X, Xu Y, Zhao H, Su Z, et al.
Cancer Sci 2019 Nov
The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma.
Yang WH, Ding CC, Sun T, Rupprecht G, Lin CC, et al.
Cell Rep 2019 Sep 3
Ginsenoside Compound K Induces Ros-Mediated Apoptosis and Autophagic Inhibition in Human Neuroblastoma Cells In Vitro and In Vivo.
Oh JM, Kim E, Chun S
Int J Mol Sci 2019 Sep 1
Concomitant targeting of Hedgehog signaling and MCL-1 synergistically induces cell death in Hedgehog-driven cancer cells.
Meister MT, Boedicker C, Linder B, Kögel D, Klingebiel T, et al.
Cancer Lett 2019 Nov 28
Palmitic Acid-Rich High-Fat Diet Exacerbates Experimental Pulmonary Fibrosis by Modulating Endoplasmic Reticulum Stress.
Chu SG, Villalba JA, Liang X, Xiong K, Tsoyi K, et al.
Am J Respir Cell Mol Biol 2019 Dec
Gedunin Degrades Aggregates of Mutant Huntingtin Protein and Intranuclear Inclusions via the Proteasomal Pathway in Neurons and Fibroblasts from Patients with Huntington's Disease.
Yang W, Xie J, Qiang Q, Li L, Lin X, et al.
Neurosci Bull 2019 Dec
Pembrolizumab in relapsed or refractory Hodgkin lymphoma: 2-year follow-up of KEYNOTE-087.
Chen R, Zinzani PL, Lee HJ, Armand P, Johnson NA, et al.
Blood 2019 Oct 3
Tumor-treating fields induce autophagy by blocking the Akt2/miR29b axis in glioblastoma cells.
Kim EH, Jo Y, Sai S, Park MJ, Kim JY, et al.
Oncogene 2019 Sep
ZBP1/DAI Drives RIPK3-Mediated Cell Death Induced by IFNs in the Absence of RIPK1.
Ingram JP, Thapa RJ, Fisher A, Tummers B, Zhang T, et al.
J Immunol 2019 Sep 1
Chloroplast-Localized Protoporphyrinogen IX Oxidase1 Is Involved in the Mitotic Cell Cycle in Arabidopsis.
Li J, Zhang F, Li Y, Yang W, Lin R, et al.
Plant Cell Physiol 2019 Nov 1
Oridonin enhances TRAIL-induced apoptosis through GALNT14-mediated DR5 glycosylation.
Jeon MY, Seo SU, Woo SM, Min KJ, Byun HS, et al.
Biochimie 2019 Oct
Rational application of the first-line chemotherapy and immune checkpoint inhibitors in advanced nonsmall cell lung cancer: A meta-analysis.
Cao R, Ma JT, Zhang SL, Sun L, Liu Y, et al.
Cancer Med 2019 Sep
Herbal formula Yangyinjiedu induces lung cancer cell apoptosis via activation of early growth response 1.
Yang W, Kang Y, Zhao Q, Bi L, Jiao L, et al.
J Cell Mol Med 2019 Sep
BOK promotes erythropoiesis in a mouse model of myelodysplastic syndrome.
Kang SH, Perales O, Michaud M, Katz SG
Ann Hematol 2019 Sep
Combined effect of alpha particles and cigarette smoke on human lung epithelial cells <i>in vitro</i>.
Lee US, Kim EH
Int J Radiat Biol 2019 Sep
EMT is the major target for okadaic acid-suppressed the development of neural crest cells in chick embryo.
Jiao YH, Liu M, Wang G, Li HY, Liu JS, et al.
Ecotoxicol Environ Saf 2019 Sep 30
Matrix Metalloproteinase 11 Is a Potential Therapeutic Target in Lung Adenocarcinoma.
Yang H, Jiang P, Liu D, Wang HQ, Deng Q, et al.
Mol Ther Oncolytics 2019 Sep 27
Protease/antiprotease network in allergy: The role of Staphylococcus aureus protease-like proteins.
Krysko O, Teufelberger A, Van Nevel S, Krysko DV, Bachert C, et al.
Allergy 2019 Nov
Cell cycle arrest in mitosis promotes interferon-induced necroptosis.
Frank T, Tuppi M, Hugle M, Dötsch V, van Wijk SJL, et al.
Cell Death Differ 2019 Oct
Author Correction: Caveolin-1 impairs PKA-DRP1-mediated remodelling of ER-mitochondria communication during the early phase of ER stress.
Bravo-Sagua R, Parra V, Ortiz-Sandoval C, Navarro-Marquez M, Rodríguez AE, et al.
Cell Death Differ 2019 Nov
Accurate elimination of superfluous attachment cells is critical for the construction of functional multicellular proprioceptors in Drosophila.
Avetisyan A, Salzberg A
Cell Death Differ 2019 Oct
Crosstalk between inflammatory mediators and endoplasmic reticulum stress in liver diseases.
Duvigneau JC, Luís A, Gorman AM, Samali A, Kaltenecker D, et al.
Cytokine 2019 Dec