Member Publications

RGD-containing elastin like polypeptide improves islet transplantation outcomes in diabetic mice.
Lee KM, Kim JH, Choi ES, Kim E, Choi SK, et al.
Acta Biomater 2019 Jun 11

Autophagy-Independent Functions of the Autophagy Machinery.
Galluzzi L, Green DR
Cell 2019 Jun 13

Selective elimination of cancer cells by the adenovirus E4orf4 protein in a Drosophila cancer model: a new paradigm for cancer therapy.
Rosen H, Sharf R, Pechkovsky A, Salzberg A, Kleinberger T, et al.
Cell Death Dis 2019 Jun 11

Development of Theragnostic Tool Using NIR Fluorescence Probe Targeting Mitochondria in Glioma Cells.
Chu Y, Shin MC, Sung J, Park J, Kim E, et al.
Bioconjug Chem 2019 Jun 10

Staphylococcus aureus Orchestrates Type 2 Airway Diseases.
Teufelberger AR, Bröker BM, Krysko DV, Bachert C, Krysko O, et al.
Trends Mol Med 2019 Jun 5

Targeting ferroptosis in rhabdomyosarcoma cells.
Dächert J, Ehrenfeld V, Habermann K, Dolgikh N, Fulda S, et al.
Int J Cancer 2019 Jun 7

Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against Mycobacterium tuberculosis.
Kim EW, De Leon A, Jiang Z, Radu RA, Martineau AR, et al.
mSphere 2019 Jun 5

Combined effect of alpha particles and cigarette smoke on human lung epithelial cells <i>in vitro</i>.
Lee US, Kim EH
Int J Radiat Biol 2019 Jun 12

Ubiquitin Ligases cIAP1 and cIAP2 Limit Cell Death to Prevent Inflammation.
Zhang J, Webster JD, Dugger DL, Goncharov T, Roose-Girma M, et al.
Cell Rep 2019 May 28

Kinesin-14 motor protein KIFC1 participates in DNA synthesis and chromatin maintenance.
Wei YL, Yang WX
Cell Death Dis 2019 May 24

Concomitant targeting of BCL2 with venetoclax and MAPK signaling with cobimetinib in acute myeloid leukemia models.
Han L, Zhang Q, Dail M, Shi C, Cavazos A, et al.
Haematologica 2019 May 23

Mitophagy in Cancer: A Tale of Adaptation.
Vara-Perez M, Felipe-Abrio B, Agostinis P
Cells 2019 May 22

The paracrine effects of fibroblasts on Doxorubicin-treated breast cancer cells.
Fourie C, Davis T, Kriel J, Engelbrecht AM
Exp Cell Res 2019 Aug 15

IRF2 transcriptionally induces <i>GSDMD</i> expression for pyroptosis.
Kayagaki N, Lee BL, Stowe IB, Kornfeld OS, O'Rourke K, et al.
Sci Signal 2019 May 21

Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.
Carreras-Sureda A, Jaña F, Urra H, Durand S, Mortenson DE, et al.
Nat Cell Biol 2019 Jun

Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion.
Friedmann Angeli JP, Krysko DV, Conrad M
Nat Rev Cancer 2019 May 17

The Coming Decade of Cell Death Research: Five Riddles.
Green DR
Cell 2019 May 16

Risk of dermatologic and mucosal adverse events associated with PD-1/PD-L1 inhibitors in cancer patients: A meta-analysis of randomized controlled trials.
Yang W, Li S, Yang Q
Medicine (Baltimore) 2019 May

Involvement of TREK-1 Channel in Cell Viability of H9c2 Rat Cardiomyoblasts Affected by Bupivacaine and Lipid Emulsion.
Yang JH, Siregar AS, Kim EJ, Nyiramana MM, Shin EJ, et al.
Cells 2019 May 14

PD-L1 expression and tumor mutational burden status for prediction of response to chemotherapy and targeted therapy in non-small cell lung cancer.
Chen Y, Liu Q, Chen Z, Wang Y, Yang W, et al.
J Exp Clin Cancer Res 2019 May 14

Transcriptomic Analysis Reveals a Comprehensive Calcium- and Phytohormone-Dominated Signaling Response in <i>Leymus chinensis</i> Self-Incompatibility.
Chen S, Jia J, Cheng L, Zhao P, Qi D, et al.
Int J Mol Sci 2019 May 13

Targeting monocyte-intrinsic enhancer reprogramming improves immunotherapy efficacy in hepatocellular carcinoma.
Liu M, Zhou J, Liu X, Feng Y, Yang W, et al.
Gut 2019 May 10

Redox (phospho)lipidomics of signaling in inflammation and programmed cell death.
Tyurina YY, St Croix CM, Watkins SC, Watson AM, Epperly MW, et al.
J Leukoc Biol 2019 May 9

nNOS/GSNOR interaction contributes to skeletal muscle differentiation and homeostasis.
Montagna C, Rizza S, Cirotti C, Maiani E, Muscaritoli M, et al.
Cell Death Dis 2019 May 1

A new split-luciferase complementation assay identifies pentachlorophenol as an inhibitor of apoptosome formation.
Tashakor A, H-Dehkordi M, O'Connell E, Gomez Ganau S, Gozalbes R, et al.
FEBS Open Bio 2019 Apr 29

Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites.
McNamara DE, Dovey CM, Hale AT, Quarato G, Grace CR, et al.
Cell Chem Biol 2019 Mar 29

Matrix Metalloproteinase 11 Is a Potential Therapeutic Target in Lung Adenocarcinoma.
Yang H, Jiang P, Liu D, Wang HQ, Deng Q, et al.
Mol Ther Oncolytics 2019 Sep 27

Complement C5b-9 and Cancer: Mechanisms of Cell Damage, Cancer Counteractions, and Approaches for Intervention.
Fishelson Z, Kirschfink M
Front Immunol 2019

Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1.
He M, Chaurushiya MS, Webster JD, Kummerfeld S, Reja R, et al.
Science 2019 Apr 19

[Role of Vascular Niche of Bone Marrow in the Development of MLL-AF9 Induced Acute Myclaid Leukemia].
Zhao M, Gong YM, Yang WZ, Cheng H, Cheng T, et al.
Zhongguo Shi Yan Xue Ye Xue Za Zhi 2019 Apr

Hydrogen sulfide protects H9c2 cardiomyoblasts against H2O2-induced apoptosis.
Zhang YE, Huang GQ, Wu B, Lin XD, Yang WZ, et al.
Braz J Med Biol Res 2019

DR4-Ser424 <i>O</i>-GlcNAcylation Promotes Sensitization of TRAIL-Tolerant Persisters and TRAIL-Resistant Cancer Cells to Death.
Lee H, Oh Y, Jeon YJ, Lee SY, Kim H, et al.
Cancer Res 2019 Jun 1

NSC-34 motor neuron-like cells are sensitized to ferroptosis upon differentiation.
Martinez AM, Mirkovic J, Stanisz ZA, Patwari FS, Yang WS, et al.
FEBS Open Bio 2019 Apr

The ARTS of Cell Death.
Koren E, Fuchs Y
J Cell Death 2019

Autophagy as a molecular target for cancer treatment.
Kocaturk NM, Akkoc Y, Kig C, Bayraktar O, Gozuacik D, et al.
Eur J Pharm Sci 2019 Jun 15

Minocycline mitigates the effect of neonatal hypoxic insult on human brain organoids.
Boisvert EM, Means RE, Michaud M, Madri JA, Katz SG, et al.
Cell Death Dis 2019 Apr 11

NEAT1 promotes myocardial ischemia-reperfusion injury via activating the MAPK signaling pathway.
Du XJ, Wei J, Tian D, Yan C, Hu P, et al.
J Cell Physiol 2019 Apr 4

Lysosomal Pathways and Autophagy Distinctively Control Endothelial Cell Behavior to Affect Tumor Vasculature.
Schaaf MB, Houbaert D, Meçe O, To SK, Ganne M, et al.
Front Oncol 2019

Reversible induction of mitophagy by an optogenetic bimodular system.
D'Acunzo P, Strappazzon F, Caruana I, Meneghetti G, Di Rita A, et al.
Nat Commun 2019 Apr 4

The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors.
Mahameed M, Wilhelm T, Darawshi O, Obiedat A, Tommy WS, et al.
Cell Death Dis 2019 Apr 1

The role of lncRNA MSC-AS1/miR-29b-3p axis-mediated CDK14 modulation in pancreatic cancer proliferation and Gemcitabine-induced apoptosis.
Sun Y, Wang P, Yang W, Shan Y, Zhang Q, et al.
Cancer Biol Ther 2019

Melatonin receptor depletion suppressed hCG-induced testosterone expression in mouse Leydig cells.
Gao Y, Wu X, Zhao S, Zhang Y, Ma H, et al.
Cell Mol Biol Lett 2019

PERK regulates Nrf2/ARE antioxidant pathway against dibutyl phthalate-induced mitochondrial damage and apoptosis dependent of reactive oxygen species in mouse spermatocyte-derived cells.
Zhang G, Yang W, Jiang F, Zou P, Zeng Y, et al.
Toxicol Lett 2019 Jun 15

Structure and Neuroprotective Effect of Polysaccharide from Viscera Autolysates of Squid <i>Ommastrephes bartrami</i>.
Ye P, Li P, Yang W, Zhao Y, Zhao Y, et al.
Mar Drugs 2019 Mar 22

Controlling metastatic cancer: the role of phytochemicals in cell signaling.
Kapinova A, Kubatka P, Liskova A, Baranenko D, Kruzliak P, et al.
J Cancer Res Clin Oncol 2019 May

Mitochondrial origins of fractional control in regulated cell death.
Santos LC, Vogel R, Chipuk JE, Birtwistle MR, Stolovitzky G, et al.
Nat Commun 2019 Mar 21

Elevated FPR confers to radiochemoresistance and predicts clinical efficacy and outcome of metastatic colorectal cancer patients.
Chen QG, Zhang L, Sun F, Li SQ, You XH, et al.
Aging (Albany NY) 2019 Mar 21

Protease/antiprotease network in allergy: The role of Staphylococcus aureus protease-like proteins.
Krysko O, Teufelberger A, Van Nevel S, Krysko DV, Bachert C, et al.
Allergy 2019 Mar 19

Morin enhances auranofin anticancer activity by up-regulation of DR4 and DR5 and modulation of Bcl-2 through reactive oxygen species generation in Hep3B human hepatocellular carcinoma cells.
Hwang-Bo H, Lee WS, Nagappan A, Kim HJ, Panchanathan R, et al.
Phytother Res 2019 May

Korean Red ginseng extract inhibits glioblastoma propagation by blocking the Wnt signaling pathway.
Ham SW, Kim JK, Jeon HY, Kim EJ, Jin X, et al.
J Ethnopharmacol 2019 May 23

β-Apopicropodophyllin functions as a radiosensitizer targeting ER stress in non-small cell lung cancer.
Kim JY, Cho JH, Kim EM, Shin HJ, Hwang SG, et al.
Biomed Pharmacother 2019 May

Targeting Epidermal Growth Factor Receptor in Non-Small-Cell-Lung Cancer: Current State and Future Perspective.
Bao SM, Hu QH, Yang WT, Wang Y, Tong YP, et al.
Anticancer Agents Med Chem 2019 Mar 13

Combination immunotherapy with IL-4 Pseudomonas exotoxin and IFN-α and IFN-γ mediate antitumor effects in vitro and in a mouse model of human ovarian cancer.
Green DS, Husain SR, Johnson CL, Sato Y, Han J, et al.
Immunotherapy 2019 Apr

Bafilomycin-A1 and ML9 exert different lysosomal actions to induce cell death.
Shaikh S, Nandy SK, Canti C, Lavandero S
Curr Mol Pharmacol 2019 Mar 8

A Novel Lactate Dehydrogenase Inhibitor, 1-(Phenylseleno)-4-(Trifluoromethyl) Benzene, Suppresses Tumor Growth through Apoptotic Cell Death.
Kim EY, Chung TW, Han CW, Park SY, Park KH, et al.
Sci Rep 2019 Mar 8

MERTK tyrosine kinase receptor together with TIM4 phosphatidylserine receptor mediates distinct signal transduction pathways for efferocytosis and cell proliferation.
Nishi C, Yanagihashi Y, Segawa K, Nagata S
J Biol Chem 2019 May 3

ABHD5 blunts the sensitivity of colorectal cancer to fluorouracil via promoting autophagic uracil yield.
Ou J, Peng Y, Yang W, Zhang Y, Hao J, et al.
Nat Commun 2019 Mar 6

Pro-apoptotic and pro-proliferation functions of the JNK pathway of Drosophila: roles in cell competition, tumorigenesis and regeneration.
Pinal N, Calleja M, Morata G
Open Biol 2019 Mar 29

In Situ Dendritic Cell Vaccine for Effective Cancer Immunotherapy.
Yang W, Zhu G, Wang S, Yu G, Yang Z, et al.
ACS Nano 2019 Mar 26

Inhibition of lymphatic proliferation by the selective VEGFR-3 inhibitor SAR131675 ameliorates diabetic nephropathy in db/db mice.
Hwang SD, Song JH, Kim Y, Lim JH, Kim MY, et al.
Cell Death Dis 2019 Mar 4

Anticancer Effects of Baicalein in FRO Thyroid Cancer Cells Through the Up-regulation of ERK/p38 MAPK and Akt Pathway.
Han SE, Park CH, Nam-Goong IS, Kim YI, Kim ES, et al.
In Vivo 2019 Mar-Apr

Epidermal Growth Factor Receptor-Targeted Multifunctional Photosensitizers for Bladder Cancer Imaging and Photodynamic Therapy.
Cheruku RR, Cacaccio J, Durrani FA, Tabaczynski WA, Watson R, et al.
J Med Chem 2019 Mar 14

Cytochrome <i>c</i> Deficiency Confers Apoptosome and Mitochondrial Dysfunction in African-American Men with Prostate Cancer.
Kumar R, Bhat TA, Walsh EM, Chaudhary AK, O'Malley J, et al.
Cancer Res 2019 Apr 1

Cathepsins: Potent regulators in carcinogenesis.
Khaket TP, Kwon TK, Kang SC
Pharmacol Ther 2019 Jun

Modulation of the ATM/autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells.
Beauvarlet J, Bensadoun P, Darbo E, Labrunie G, Rousseau B, et al.
Nucleic Acids Res 2019 Apr 8

Stanniocalcin‑1 promotes cell proliferation, chemoresistance and metastasis in hypoxic gastric cancer cells via Bcl‑2.
Wang Y, Qi Z, Zhou M, Yang W, Hu R, et al.
Oncol Rep 2019 Mar

TAZ stimulates liver regeneration through interleukin-6-induced hepatocyte proliferation and inhibition of cell death after liver injury.
Kim AR, Park JI, Oh HT, Kim KM, Hwang JH, et al.
FASEB J 2019 May

Interview: a conversation with Vishva M Dixit on his journey from remote African village to apoptosis, necroptosis and the inflammasome.
Dixit VM
Cell Death Differ 2019 Mar

Staying in touch: Taking a closer look at ER-Golgi contact sites.
Sassano ML, Agostinis P
J Cell Biol 2019 Mar 4

Cationic amino acid transporter PQLC2 is a potential therapeutic target in gastric cancer.
Jeung YJ, Lee K, Lee HJ, Kim E, Son MJ, et al.
Cancer Sci 2019 Apr

Autophagy and cancer stem cells: molecular mechanisms and therapeutic applications.
Nazio F, Bordi M, Cianfanelli V, Locatelli F, Cecconi F, et al.
Cell Death Differ 2019 Mar

Autophagy in endothelial cells and tumor angiogenesis.
Schaaf MB, Houbaert D, Meçe O, Agostinis P
Cell Death Differ 2019 Mar

NF-κB contributes to Smac mimetic-conferred protection from tunicamycin-induced apoptosis.
Abhari BA, McCarthy N, Agostinis P, Fulda S
Apoptosis 2019 Apr

Targeting intrinsic cell death pathways to control fungal pathogens.
Kulkarni M, Stolp ZD, Hardwick JM
Biochem Pharmacol 2019 Apr

Immune Checkpoint Inhibitor-induced Reinvigoration of Tumor-infiltrating CD8⁺ T Cells is Determined by Their Differentiation Status in Glioblastoma.
Park J, Kwon M, Kim KH, Kim TS, Hong SH, et al.
Clin Cancer Res 2019 Apr 15

Cotreatment with sorafenib and oleanolic acid induces reactive oxygen species-dependent and mitochondrial-mediated apoptotic cell death in hepatocellular carcinoma cells.
Liese J, Hinrichs TM, Lange M, Fulda S
Anticancer Drugs 2019 Mar

Human Leukocyte Antigen Class I and Programmed Death-Ligand 1 Coexpression Is an Independent Poor Prognostic Factor in Adenocarcinoma of the Lung.
Han YB, Kwon HJ, Park SY, Kim ES, Kim H, et al.
J Pathol Transl Med 2019 Mar

Preclinical pharmacodynamic evaluation of a new Src/FOSL1 inhibitor, LY-1816, in pancreatic ductal adenocarcinoma.
Yang W, Meng L, Chen K, Tian C, Peng B, et al.
Cancer Sci 2019 Apr

Heat shock protein 70 is induced by pepsin via MAPK signaling in human nasal epithelial cells.
Wang J, Zhao Y, Ren J, Xu Y, Yang W, et al.
Eur Arch Otorhinolaryngol 2019 Mar

Long non‑coding RNA DLX6‑AS1 is associated with malignant progression and promotes proliferation and invasion in esophageal squamous cell carcinoma.
Wang M, Li Y, Yang Y, Liu X, Zang M, et al.
Mol Med Rep 2019 Mar

Amelioration of amyloid β-FcγRIIb neurotoxicity and tau pathologies by targeting LYN.
Gwon Y, Kim SH, Kim HT, Kam TI, Park J, et al.
FASEB J 2019 Mar

Casticin inhibits growth and enhances ionizing radiation-induced apoptosis through the suppression of STAT3 signaling cascade.
Lee JH, Kim C, Ko JH, Jung YY, Jung SH, et al.
J Cell Biochem 2019 Jun

Up-regulation of P-gp via NF-κB activation confers protection against oxidative damage in the retinal pigment epithelium cells.
Feng Q, Yang W, Gao Z, Ruan X, Zhang Y, et al.
Exp Eye Res 2019 Apr

Knockdown of PSMC3IP suppresses the proliferation and xenografted tumorigenesis of hepatocellular carcinoma cell.
Ding J, Li Y, Fan H, Xu W, Gao R, et al.
J Cell Biochem 2019 Apr

Comparison of main molecular markers involved in autophagy and apoptosis pathways between spermatozoa of infertile men with varicocele and fertile individuals.
Foroozan-Broojeni S, Tavalaee M, Lockshin RA, Zakeri Z, Abbasi H, et al.
Andrologia 2019 Mar

About canonical, non-canonical and immunogenic cell death: Basic mechanisms and translational applications: A meeting report of the International Cell Death Society.
Zakeri Z, Lockshin RA, Diederich M
Biochem Pharmacol 2019 Apr

Loss of receptor interacting protein kinases 3 and caspase-8 augments intrinsic apoptosis in tubular epithelial cell and promote kidney ischaemia-reperfusion injury.
Sung B, Su Y, Jiang J, Mcleod P, Liu W, et al.
Nephrology (Carlton) 2019 Jun

Clinical significance of isoagglutinin titre with the current desensitization protocol in ABO-incompatible kidney transplantation.
Baek CH, Kim H, Yang WS, Han DJ, Park SK, et al.
Nephrology (Carlton) 2019 Jun

Remote organ failure in acute kidney injury.
Kao CC, Yang WS, Fang JT, Liu KD, Wu VC, et al.
J Formos Med Assoc 2019 May

TP53 gain-of-function mutation promotes inflammation in glioblastoma.
Ham SW, Jeon HY, Jin X, Kim EJ, Kim JK, et al.
Cell Death Differ 2019 Mar