Member Publications

An emerging role for nanomaterials in increasing immunogenicity of cancer cell death.
Mishchenko T, Mitroshina E, Balalaeva I, Krysko O, Vedunova M, et al.
Biochim Biophys Acta Rev Cancer 2018 Dec 5

Interferons Transcriptionally Up-Regulate MLKL Expression in Cancer Cells.
Knuth AK, Rösler S, Schenk B, Kowald L, van Wijk SJL, et al.
Neoplasia 2018 Dec 3

Casticin inhibits growth and enhances ionizing radiation-induced apoptosis through the suppression of STAT3 signaling cascade.
Lee JH, Kim C, Ko JH, Jung YY, Jung SH, et al.
J Cell Biochem 2018 Dec 5

The natural polyphenol curcumin induces apoptosis by suppressing STAT3 signaling in esophageal squamous cell carcinoma.
Liu Y, Wang X, Zeng S, Zhang X, Zhao J, et al.
J Exp Clin Cancer Res 2018 Dec 5

To the edge of cell death and back.
Gong YN, Crawford JC, Heckmann BL, Green DR
FEBS J 2018 Dec 1

Up-regulation of P-gp via NF-κB activation confers protection against oxidative damage in the retinal pigment epithelium cells.
Feng Q, Yang W, Gao Z, Ruan X, Zhang Y, et al.
Exp Eye Res 2018 Nov 26

TBK1 and IKKε restrain cell death.
Heger K, Dixit VM
Nat Cell Biol 2018 Dec

Identification of 5-(2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Derivatives as a New Class of Receptor-Interacting Protein Kinase 1 (RIPK1) Inhibitors, Which Showed Potent Activity in a Tumor Metastasis Model.
Li Y, Xiong Y, Zhang G, Zhang L, Yang W, et al.
J Med Chem 2018 Nov 27

Calcimimetic restores diabetic peripheral neuropathy by ameliorating apoptosis and improving autophagy.
Chung YC, Lim JH, Oh HM, Kim HW, Kim MY, et al.
Cell Death Dis 2018 Nov 26

Prolonged MEK inhibition leads to acquired resistance and increased invasiveness in KRAS mutant gastric cancer.
Choi KM, Cho E, Kim E, Shin JH, Kang M, et al.
Biochem Biophys Res Commun 2018 Dec 9

Gene Therapy in Head and Neck Cancer.
Farmer ZL, Kim ES, Carrizosa DR
Oral Maxillofac Surg Clin North Am 2019 Feb

[Impact of HIV and <i>Mycobacterium tuberculosis</i> co-infection on related mortality].
Zheng ZG, Geng WK, Lu ZZ, Li JJ, Zhou CX, et al.
Zhonghua Liu Xing Bing Xue Za Zhi 2018 Oct 10

Crosstalk between inflammatory mediators and endoplasmic reticulum stress in liver diseases.
Duvigneau JC, Luís A, Gorman AM, Samali A, Kaltenecker D, et al.
Cytokine 2018 Nov 14

Disulfiram Copper Nanoparticles Prepared with a Stabilized Metal Ion Ligand Complex Method for Treating Drug-Resistant Prostate Cancers.
Chen W, Yang W, Chen P, Huang Y, Li F, et al.
ACS Appl Mater Interfaces 2018 Nov 16

Evaluating the Remote Control of Programmed Cell Death, with or without a Compensatory Cell Proliferation.
Dou X, Chen L, Lei M, Zellmer L, Jia Q, et al.
Int J Biol Sci 2018

Ribosomal protein S6 kinase 1 promotes the survival of photoreceptors in retinitis pigmentosa.
Lin B, Xiong G, Yang W
Cell Death Dis 2018 Nov 15

PLOD3 promotes lung metastasis via regulation of STAT3.
Baek JH, Yun HS, Kwon GT, Kim JY, Lee CW, et al.
Cell Death Dis 2018 Nov 15

Increased incidence, morbidity and mortality rates for lung cancer in women in Brazil between 2000 and 2014: An analysis of three types of sources of secondary data.
Costa GJ, de Mello MJG, Ferreira CG, Bergmann A, Thuler LCS, et al.
Lung Cancer 2018 Nov

The prognostic role of PD-L1 expression for survival in head and neck squamous cell carcinoma: A systematic review and meta-analysis.
Yang WF, Wong MCM, Thomson PJ, Li KY, Su YX, et al.
Oral Oncol 2018 Nov

Association of Resistin Gene Polymorphisms with Oral Squamous Cell Carcinoma Progression and Development.
Yang WH, Wang SJ, Chang YS, Su CM, Yang SF, et al.
Biomed Res Int 2018

Water-extracted branch of Cinnamomum cassia promotes lung cancer cell apoptosis by inhibiting pyruvate dehydrogenase kinase activity.
Lee EJ, Chung TW, Lee JH, Kim BS, Kim EY, et al.
J Pharmacol Sci 2018 Oct

Differential involvement of TAK1, RIPK1 and NF-κB signaling in Smac mimetic-induced cell death in breast cancer cells.
Schmidt N, Kowald L, van Wijk SJL, Fulda S
Biol Chem 2018 Nov 30

ARTS mediates apoptosis and regeneration of the intestinal stem cell niche.
Koren E, Yosefzon Y, Ankawa R, Soteriou D, Jacob A, et al.
Nat Commun 2018 Nov 2

Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis.
Moon S, Im SK, Kim N, Youn H, Park UH, et al.
Cell Death Dis 2018 Nov 2

Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during <i>Yersinia</i> infection.
Sarhan J, Liu BC, Muendlein HI, Li P, Nilson R, et al.
Proc Natl Acad Sci U S A 2018 Nov 13

Comparative Proteomic Profiling of Tumor-Associated Proteins in Human Gastric Cancer Cells Treated with Pectolinarigenin.
Lee HJ, Venkatarame Gowda Saralamma V, Kim SM, Ha SE, Vetrivel P, et al.
Nutrients 2018 Oct 30

Cyclophilin D Phosphorylation is Critical for Mitochondrial Calcium Uniporter Regulated Permeability Transition Pore Sensitivity.
Dhingra R, Lieberman B, Kirshenbaum LA
Cardiovasc Res 2018 Oct 31

EUS-guided irreversible electroporation using endoscopic needle-electrode in porcine pancreas.
Lee JM, Choi HS, Chun HJ, Kim ES, Keum B, et al.
Surg Endosc 2018 Oct 29

Endothelial cells release cardioprotective exosomes that may contribute to ischaemic preconditioning.
Davidson SM, Riquelme JA, Zheng Y, Vicencio JM, Lavandero S, et al.
Sci Rep 2018 Oct 26

Leptin in depression: a potential therapeutic target.
Ge T, Fan J, Yang W, Cui R, Li B, et al.
Cell Death Dis 2018 Oct 26

Knockdown of PSMC3IP suppresses the proliferation and xenografted tumorigenesis of hepatocellular carcinoma cell.
Ding J, Li Y, Fan H, Xu W, Gao R, et al.
J Cell Biochem 2018 Oct 25

Cepharanthine Enhances TRAIL-Mediated Apoptosis Through STAMBPL1-Mediated Downregulation of Survivin Expression in Renal Carcinoma Cells.
Shahriyar SA, Woo SM, Seo SU, Min KJ, Kwon TK, et al.
Int J Mol Sci 2018 Oct 22

C-27-carboxylated oleanane triterpenoids up-regulate TRAIL DISC assembly via p38 MAPK and CHOP-mediated DR5 expression in human glioblastoma cells.
Byun HS, Zhou W, Park I, Kang K, Lee SR, et al.
Biochem Pharmacol 2018 Dec

HSP70 Acetylation Prevents Combined mTORC1/2 Inhibitor and Curcumin Treatment-Induced Apoptosis.
Seo SU, Min KJ, Woo SM, Seo JH, Kwon TK, et al.
Molecules 2018 Oct 24

Comparison of main molecular markers involved in autophagy and apoptosis pathways between spermatozoa of infertile men with varicocele and fertile individuals.
Foroozan-Broojeni S, Tavalaee M, Lockshin RA, Zakeri Z, Abbasi H, et al.
Andrologia 2018 Oct 23

Programmed Necrosis and Disease:We interrupt your regular programming to bring you necroinflammation.
Kim EH, Wong SW, Martinez J
Cell Death Differ 2018 Oct 22

Crashing the computer: apoptosis vs. necroptosis in neuroinflammation.
Heckmann BL, Tummers B, Green DR
Cell Death Differ 2018 Oct 19

Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer.
Shin D, Kim EH, Lee J, Roh JL
Free Radic Biol Med 2018 Dec

Phosphoprotein patterns predict trametinib responsiveness and optimal trametinib sensitisation strategies in melanoma.
Rožanc J, Sakellaropoulos T, Antoranz A, Guttà C, Podder B, et al.
Cell Death Differ 2018 Oct 15

Copper-induced cell death and the protective role of glutathione: the implication of impaired protein folding rather than oxidative stress.
Saporito-Magriñá CM, Musacco-Sebio RN, Andrieux G, Kook L, Orrego MT, et al.
Metallomics 2018 Oct 12

Selective toxicity of tumor treating fields to melanoma: an in vitro and in vivo study.
Jo Y, Hwang SG, Jin YB, Sung J, Jeong YK, et al.
Cell Death Discov 2018

Identification of a novel biomarker in tangeretin‑induced cell death in AGS human gastric cancer cells.
Yumnam S, Raha S, Kim SM, Venkatarame Gowda Saralamma V, Lee HJ, et al.
Oncol Rep 2018 Dec

Altered mRNA expression levels of the major components of sphingolipid metabolism, ceramide synthases and their clinical implication in colorectal cancer.
Jang SW, Park WJ, Min H, Kwon TK, Baek SK, et al.
Oncol Rep 2018 Dec

<i>Drosophila</i> HUWE1 Ubiquitin Ligase Regulates Endoreplication and Antagonizes JNK Signaling During Salivary Gland Development.
Yanku Y, Bitman-Lotan E, Zohar Y, Kurant E, Zilke N, et al.
Cells 2018 Sep 26

IP₃ receptor blockade restores autophagy and mitochondrial function in skeletal muscle fibers of dystrophic mice.
Valladares D, Utreras-Mendoza Y, Campos C, Morales C, Diaz-Vegas A, et al.
Biochim Biophys Acta Mol Basis Dis 2018 Nov

Autophagy mediates calcium-sensing receptor-induced TNFα production in human preadipocytes.
Mattar P, Bravo-Sagua R, Tobar N, Fuentes C, Troncoso R, et al.
Biochim Biophys Acta Mol Basis Dis 2018 Nov

MiR-1260b inhibitor enhances the chemosensitivity of colorectal cancer cells to fluorouracil by targeting PDCD4/IGF1.
Zhao J, Cao J, Zhou L, Du Y, Zhang X, et al.
Oncol Lett 2018 Oct

Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells.
Zielke S, Meyer N, Mari M, Abou-El-Ardat K, Reggiori F, et al.
Cell Death Dis 2018 Sep 24

Rapamycin and fasting sustain autophagy response activated by ischemia/reperfusion injury and promote retinal ganglion cell survival.
Russo R, Varano GP, Adornetto A, Nazio F, Tettamanti G, et al.
Cell Death Dis 2018 Sep 24

The Unfolded Protein Response in Breast Cancer.
McGrath EP, Logue SE, Mnich K, Deegan S, Jäger R, et al.
Cancers (Basel) 2018 Sep 21

Autophagy-dependent cell death - where, how and why a cell eats itself to death.
Bialik S, Dasari SK, Kimchi A
J Cell Sci 2018 Sep 20

About canonical, non-canonical and immunogenic cell death: Basic mechanisms and translational applications: A meeting report of the International Cell Death Society.
Zakeri Z, Lockshin RA, Diederich M
Biochem Pharmacol 2018 Sep 14

RAB-35 and ARF-6 GTPases Mediate Engulfment and Clearance Following Linker Cell-Type Death.
Kutscher LM, Keil W, Shaham S
Dev Cell 2018 Oct 22

Activation of α7 nicotinic acetylcholine receptor alleviates Aβ_1-42-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.
Chang KW, Zong HF, Ma KG, Zhai WY, Yang WN, et al.
Neurochem Int 2018 Nov

Influence of silibinin and β-β-dimethylacrylshikonin on chordoma cells.
Zohreh J, Alexander S, Ines A, Florian K, Birgit L, et al.
Phytomedicine 2018 Oct 1

The Possible Role of Neurobeachin in Extinction of Contextual Fear Memory.
Lee B, Bang E, Yang WS, Paydar A, Ha GE, et al.
Sci Rep 2018 Sep 13

Caveolin-1 impairs PKA-DRP1-mediated remodelling of ER-mitochondria communication during the early phase of ER stress.
Bravo-Sagua R, Parra V, Ortiz-Sandoval C, Navarro-Marquez M, Rodríguez AE, et al.
Cell Death Differ 2018 Sep 12

Soft Coral <i>Dendronephthya puetteri</i> Extract Ameliorates Inflammations by Suppressing Inflammatory Mediators and Oxidative Stress in LPS-Stimulated Zebrafish.
Kim EA, Ding Y, Yang HW, Heo SJ, Lee SH, et al.
Int J Mol Sci 2018 Sep 10

FAF1 mediates necrosis through JNK1-mediated mitochondrial dysfunction leading to retinal degeneration in the ganglion cell layer upon ischemic insult.
Yu C, Kim BS, Park M, Do YJ, Kong YY, et al.
Cell Commun Signal 2018 Sep 10

Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model.
Choi SH, Bylykbashi E, Chatila ZK, Lee SW, Pulli B, et al.
Science 2018 Sep 7

Involvement of Up-Regulation of DR5 Expression and Down-Regulation of c-FLIP in Niclosamide-Mediated TRAIL Sensitization in Human Renal Carcinoma Caki Cells.
Yun JM, Woo SM, Seo SU, Min KJ, Kim DE, et al.
Molecules 2018 Sep 5

TNFα sensitizes hepatocytes to FasL-induced apoptosis by NFκB-mediated Fas upregulation.
Faletti L, Peintner L, Neumann S, Sandler S, Grabinger T, et al.
Cell Death Dis 2018 Sep 5

TRIM52 plays an oncogenic role in ovarian cancer associated with NF-kB pathway.
Yang W, Liu L, Li C, Luo N, Chen R, et al.
Cell Death Dis 2018 Sep 5

Loss of RIPK3 and Caspase-8 Augments Intrinsic Apoptosis in Tubular Epithelial Cell and promote Kidney Ischemia Reperfusion Injury.
Sung B, Su Y, Jiang J, Mcleod P, Liu W, et al.
Nephrology (Carlton) 2018 Sep 3

Apoptosis Signal-regulating Kinase 1 Silencing on Astroglial Inflammasomes in an Experimental Model of Ischemic Stroke.
Cheon SY, Kim EJ, Kim SY, Kim JM, Kam EH, et al.
Neuroscience 2018 Oct 15

Whi2 signals low leucine availability to halt yeast growth and cell death.
Teng X, Yau E, Sing C, Hardwick JM
FEMS Yeast Res 2018 Dec 1

Licochalcone C induced apoptosis in human oral squamous cell carcinoma cells by regulation of the JAK2/STAT3 signaling pathway.
Oh HN, Seo JH, Lee MH, Kim C, Kim E, et al.
J Cell Biochem 2018 Dec

Pyrethroid bifenthrin induces oxidative stress, neuroinflammation, and neuronal damage, associated with cognitive and memory impairment in murine hippocampus.
Gargouri B, Yousif NM, Attaai A, Bouchard M, Chtourou Y, et al.
Neurochem Int 2018 Nov

Long non-coding RNA TUG1 sponges miR-197 to enhance cisplatin sensitivity in triple negative breast cancer.
Tang T, Cheng Y, She Q, Jiang Y, Chen Y, et al.
Biomed Pharmacother 2018 Nov

Adrenomedullin Reduces Secondary Injury and Improves Outcome in Rats with Fluid Percussion Brain Injury.
Gao W, Ju YN, Chen JF, Zhou Q, Song CY, et al.
World Neurosurg 2018 Nov

Intranuclear delivery of synthetic nuclear factor-kappa B p65 reduces inflammasomes after surgery.
Cheon SY, Kim JM, Kim EJ, Kim SY, Kam EH, et al.
Biochem Pharmacol 2018 Dec

microRNAs selectively protect hub cells of the germline stem cell niche from apoptosis.
Volin M, Zohar-Fux M, Gonen O, Porat-Kuperstein L, Toledano H, et al.
J Cell Biol 2018 Nov 5

Radiosensitization by irinotecan is attributed to G2/M phase arrest, followed by enhanced apoptosis, probably through the ATM/Chk/Cdc25C/Cdc2 pathway in p53-mutant colorectal cancer cells.
Wang Y, Yang L, Zhang J, Zhou M, Shen L, et al.
Int J Oncol 2018 Oct

Protection of the myocardium against ischemia/reperfusion injury by angiotensin-(1-9) through an AT₂R and Akt-dependent mechanism.
Mendoza-Torres E, Riquelme JA, Vielma A, Sagredo AR, Gabrielli L, et al.
Pharmacol Res 2018 Sep

Effect of Productive Human Papillomavirus 16 Infection on Global Gene Expression in Cervical Epithelium.
Kang SD, Chatterjee S, Alam S, Salzberg AC, Milici J, et al.
J Virol 2018 Oct 15

Silencing GOLPH3 gene expression reverses resistance to cisplatin in HT29 colon cancer cells via multiple signaling pathways.
Zhou ZP, Wang LP, Hong ZS, Qiu CZ, Wang MZ, et al.
Int J Oncol 2018 Sep

Melatonin improves cardiac and mitochondrial function during doxorubicin-induced cardiotoxicity: A possible role for peroxisome proliferator-activated receptor gamma coactivator 1-alpha and sirtuin activity?
Govender J, Loos B, Marais E, Engelbrecht AM
Toxicol Appl Pharmacol 2018 Nov 1

Inhibition of euchromatin histone-lysine N-methyltransferase 2 sensitizes breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through reactive oxygen species-mediated activating transcription factor 4-C/EBP homologous protein-death receptor 5 pathway activation.
Kim SY, Hong M, Heo SH, Park S, Kwon TK, et al.
Mol Carcinog 2018 Nov

Single-walled carbon nanohorn aggregates promotes mitochondrial dysfunction-induced apoptosis in hepatoblastoma cells by targeting SIRT3.
Li B, Chen X, Yang W, He J, He K, et al.
Int J Oncol 2018 Sep

CISD2 inhibition overcomes resistance to sulfasalazine-induced ferroptotic cell death in head and neck cancer.
Kim EH, Shin D, Lee J, Jung AR, Roh JL, et al.
Cancer Lett 2018 Sep 28

BCL-2 selective inhibitor ABT-199 primes rhabdomyosarcoma cells to histone deacetylase inhibitor-induced apoptosis.
Heinicke U, Haydn T, Kehr S, Vogler M, Fulda S, et al.
Oncogene 2018 Sep

Structural characterization and antioxidant activities of a novel polysaccharide fraction from the fruiting bodies of Craterellus cornucopioides.
Yang WW, Wang LM, Gong LL, Lu YM, Pan WJ, et al.
Int J Biol Macromol 2018 Oct 1

MicroRNA-497 promotes proliferation and inhibits apoptosis of cardiomyocytes through the downregulation of Mfn2 in a mouse model of myocardial ischemia-reperfusion injury.
Qin L, Yang W, Wang YX, Wang ZJ, Li CC, et al.
Biomed Pharmacother 2018 Sep

mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy.
Seo SU, Woo SM, Lee HS, Kim SH, Min KJ, et al.
Oncogene 2018 Sep

Redox Dichotomy in Cell Fate Decision: Evasive Mechanism or Achilles Heel?
Pervaiz S
Antioxid Redox Signal 2018 Nov 1

Enhanced breast cancer progression by mutant p53 is inhibited by the circular RNA circ-Ccnb1.
Fang L, Du WW, Lyu J, Dong J, Zhang C, et al.
Cell Death Differ 2018 Dec

Prognostic value of systemic immune-inflammation index in patients with advanced non-small-cell lung cancer.
Guo D, Zhang J, Jing W, Liu J, Zhu H, et al.
Future Oncol 2018 Oct

Clinical implication of programmed cell death-1 ligand-1 expression in tonsillar squamous cell carcinoma in association with intratumoral heterogeneity, human papillomavirus, and epithelial-to-mesenchymal transition.
Kwon MJ, Rho YS, Nam ES, Cho SJ, Park HR, et al.
Hum Pathol 2018 Oct

BIX-01294 sensitizes renal cancer Caki cells to TRAIL-induced apoptosis through downregulation of survivin expression and upregulation of DR5 expression.
Woo SM, Seo SU, Min KJ, Kwon TK
Cell Death Discov 2018 Dec

Cross Talk Between Cellular Redox State and the Antiapoptotic Protein Bcl-2.
Pohl SÖ, Agostino M, Dharmarajan A, Pervaiz S
Antioxid Redox Signal 2018 Nov 1

Therapeutic opportunities based on caspase modulation.
Fulda S
Semin Cell Dev Biol 2018 Oct

Reactive Oxygen Species and Oncoprotein Signaling-A Dangerous Liaison.
Chong SJF, Lai JXH, Eu JQ, Bellot GL, Pervaiz S, et al.
Antioxid Redox Signal 2018 Dec 1