Member Publications

G-MDSCs promote aging-related cardiac fibrosis by activating myofibroblasts and preventing senescence.
Sun SN, Ni SH, Li Y, Liu X, Deng JP, et al.
Cell Death Dis 2021 Jun 8
Single-cell transcriptomic analyses of cardiac immune cells reveal that Rel-driven CD72-positive macrophages induce cardiomyocyte injury.
Ni SH, Xu JD, Sun SN, Li Y, Zhou Z, et al.
Cardiovasc Res 2021 Jun 8
Mitochondrial Autophagy and Cell Survival is Regulated by the Circadian Clock Gene in Cardiac Myocytes during Ischemic Stress.
Rabinovich-Nikitin I, Rasouli M, Reitz CJ, Posen I, Margulets V, et al.
Autophagy 2021 Jun 4
Nano-Sized Hydroxyapatite Induces Apoptosis and Osteogenic Differentiation of Vascular Smooth Muscle Cells via JNK/c-JUN Pathway.
Liu Q, Xiang P, Chen M, Luo Y, Zhao Y, et al.
Int J Nanomedicine 2021
Potent Antimicrobial and Antibiofilm Activities of Feleucin-K3 Analogs Modified by α-(4-Pentenyl)-Ala against Multidrug-Resistant Bacteria.
Guo X, Yan T, Rao J, Yue X, Pei X, et al.
Biomolecules 2021 May 19
A Small Molecule Antagonist of PD-1/PD-L1 Interactions Acts as an Immune Checkpoint Inhibitor for NSCLC and Melanoma Immunotherapy.
Wang Y, Gu T, Tian X, Li W, Zhao R, et al.
Front Immunol 2021
NSrp70 is a lymphocyte-essential splicing factor that controls thymocyte development.
Kim CH, Park SM, Lee SJ, Kim YD, Jang SH, et al.
Nucleic Acids Res 2021 Jun 4
Low PDCD4 Expression Is Associated With Poor Prognosis of Colorectal Carcinoma.
Kim JY, Lee H, Kim EK, Lee WM, Hong YO, et al.
Appl Immunohistochem Mol Morphol 2021 May 24
SIRT1-autophagy axis inhibits excess iron-induced ferroptosis of foam cells and subsequently increases IL-1Β and IL-18.
Su G, Yang W, Wang S, Geng C, Guan X, et al.
Biochem Biophys Res Commun 2021 Jul 5
Anti-PD-1 Immunotherapy and Bee Venom for Relapsed and Refractory Liposarcoma: A Case Report.
Yang W, Zhang Y, Yang G, Geng Y, Chen D, et al.
Front Oncol 2021
Inhibition of CCL7 derived from Mo-MDSCs prevents metastatic progression from latency in colorectal cancer.
Ren X, Xiao J, Zhang W, Wang F, Yan Y, et al.
Cell Death Dis 2021 May 13
AKR1C3 decreased CML sensitivity to Imatinib in bone marrow microenvironment via dysregulation of miR-379-5p.
Pan D, Yang W, Zeng Y, Li W, Wang K, et al.
Cell Signal 2021 Aug
CircRNA_2646 functions as a ceRNA to promote progression of esophageal squamous cell carcinoma via inhibiting miR-124/PLP2 signaling pathway.
Zeng B, Liu Z, Zhu H, Zhang X, Yang W, et al.
Cell Death Discov 2021 May 11
M2 macrophage-derived exosomal long non-coding RNA AGAP2-AS1 enhances radiotherapy immunity in lung cancer by reducing microRNA-296 and elevating NOTCH2.
Zhang F, Sang Y, Chen D, Wu X, Wang X, et al.
Cell Death Dis 2021 May 10
Epidemiology of tongue squamous cell carcinoma: A retrospective cohort study.
da Silva Souto AC, Vieira Heimlich F, Lima de Oliveira L, Bergmann A, Dias FL, et al.
Oral Dis 2021 May 8
Prognostic and immunological potential of PPM1G in hepatocellular carcinoma.
Lin YR, Yang WJ, Yang GW
Aging (Albany NY) 2021 May 5
Hemistepsin a Induces Apoptosis of Hepatocellular Carcinoma Cells by Downregulating STAT3.
Cho IJ, Kim JK, Kim EO, Park SM, Kim SC, et al.
Int J Mol Sci 2021 Apr 29
Lumican Inhibits Osteoclastogenesis and Bone Resorption by Suppressing Akt Activity.
Lee JY, Kim DA, Kim EY, Chang EJ, Park SJ, et al.
Int J Mol Sci 2021 Apr 29
Comprehensive RNA-Seq Analysis of Potential Therapeutic Targets of Gan-Dou-Fu-Mu Decoction for Treatment of Wilson Disease Using a Toxic Milk Mouse Model.
Wei T, Hao W, Tang L, Wu H, Huang S, et al.
Front Pharmacol 2021
BNIP3 promotes HIF-1α-driven melanoma growth by curbing intracellular iron homeostasis.
Vara-Pérez M, Rossi M, Van den Haute C, Maes H, Sassano ML, et al.
EMBO J 2021 May 17
The Anti-Cancer Effects of a Zotarolimus and 5-Fluorouracil Combination Treatment on A549 Cell-Derived Tumors in BALB/c Nude Mice.
Wu CF, Wu CY, Chiou RY, Yang WC, Lin CF, et al.
Int J Mol Sci 2021 Apr 27
Molecular Mechanisms of Apoptosis Induction and Its Regulation by Fatty Acids in Pancreatic β-Cells.
Šrámek J, Němcová-Fürstová V, Kovář J
Int J Mol Sci 2021 Apr 20
Cyclin-Dependent Kinase Inhibitor BMI-1026 Induces Apoptosis by Downregulating Mcl-1 (L) and c-FLIP (L) and Inactivating p-Akt in Human Renal Carcinoma Cells.
Kim DE, Lee J, Park JW, Kang H, Nam YR, et al.
Int J Mol Sci 2021 Apr 20
Clusterin Deficiency Exacerbates Hyperoxia-Induced Acute Lung Injury.
Hong JY, Kim MN, Kim EG, Lee JW, Kim HR, et al.
Cells 2021 Apr 19
Mechanistic connections between mitochondrial biology and regulated cell death.
Chipuk JE, Mohammed JN, Gelles JD, Chen Y
Dev Cell 2021 May 3
DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells.
Tarayrah-Ibraheim L, Maurice EC, Hadary G, Ben-Hur S, Kolpakova A, et al.
Nat Commun 2021 Apr 16
FCN3 functions as a tumor suppressor of lung adenocarcinoma through induction of endoplasmic reticulum stress.
Jang H, Jun Y, Kim S, Kim E, Jung Y, et al.
Cell Death Dis 2021 Apr 15
Endothelial cell autophagy in homeostasis and cancer.
Verhoeven J, Baelen J, Agrawal M, Agostinis P
FEBS Lett 2021 Jun
Longitudinal changes in skeletal muscle mass in patients with advanced squamous cell lung cancer.
Lee J, Kim EY, Kim E, Kim KG, Kim YJ, et al.
Thorac Cancer 2021 Jun
ADCK1 activates the β-catenin/TCF signaling pathway to promote the growth and migration of colon cancer cells.
Ji Y, Liu Y, Sun C, Yu L, Wang Z, et al.
Cell Death Dis 2021 Apr 6
A Commonly Used Biocide 2-N-octyl-4-isothiazolin-3-oneInduces Blood-Brain Barrier Dysfunction via Cellular Thiol Modification and Mitochondrial Damage.
Kim D, Kim EH, Choi S, Lim KM, Tie L, et al.
Int J Mol Sci 2021 Mar 4
Case of slowly progressive type 1 diabetes mellitus with drastically reduced insulin secretory capacity after immune checkpoint inhibitor treatment for advanced renal cell carcinoma.
Yamaguchi H, Miyoshi Y, Uehara Y, Fujii K, Nagata S, et al.
Diabetol Int 2021 Apr
Novel porphyrazine-based photodynamic anti-cancer therapy induces immunogenic cell death.
Turubanova VD, Mishchenko TA, Balalaeva IV, Efimova I, Peskova NN, et al.
Sci Rep 2021 Mar 30
A review on the role of gut microbiota in immune checkpoint blockade therapy for cancer.
Kim E, Ahn H, Park H
Mamm Genome 2021 Mar 30
TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy.
Wu W, Wang X, Sun Y, Berleth N, Deitersen J, et al.
Autophagy 2021 Mar 28
MiR-628-5p Inhibits Cervical Carcinoma Proliferation and Promotes Apoptosis by Targeting VEGF.
Wu X, Lei J, Zhou B, Sun Q, Gao Y, et al.
Am J Med Sci 2021 Apr
The oncogene Mct-1 promotes progression of hepatocellular carcinoma via enhancement of Yap-mediated cell proliferation.
Yang W, Ni Y, Yang S, Ji Y, Yang X, et al.
Cell Death Discov 2021 Mar 22
Nifuroxazide improves insulin secretion and attenuates high glucose-induced inflammation and apoptosis in INS-1 cells.
Liu JY, Zhang YC, Xie RR, Song LN, Yang WL, et al.
Eur J Pharmacol 2021 May 15
hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.
Wan X, Zhu L, Zhao L, Peng L, Xiong J, et al.
Cell Death Dis 2021 Mar 19
Dysregulation of miR-23b-5p promotes cell proliferation via targeting FOXM1 in hepatocellular carcinoma.
Yang X, Yang S, Song J, Yang W, Ji Y, et al.
Cell Death Discov 2021 Mar 15
The Hippo Pathway Effector YAP Promotes Ferroptosis via the E3 Ligase SKP2.
Yang WH, Lin CC, Wu J, Chao PY, Chen K, et al.
Mol Cancer Res 2021 Jun
Picornavirus 3C - a protease ensuring virus replication and subverting host responses.
Yi J, Peng J, Yang W, Zhu G, Ren J, et al.
J Cell Sci 2021 Mar 10
Cellular senescence: Silent operator and therapeutic target in cancer.
Ramu D, Shan TW, Hirpara JL, Pervaiz S
IUBMB Life 2021 Mar
PD-L1+ neutrophils contribute to injury-induced infection susceptibility.
Thanabalasuriar A, Chiang AJ, Morehouse C, Camara M, Hawkins S, et al.
Sci Adv 2021 Mar
The CDT of Helicobacter hepaticus induces pro-survival autophagy and nucleoplasmic reticulum formation concentrating the RNA binding proteins UNR/CSDE1 and P62/SQSTM1.
He W, Azzi-Martin L, Velasco V, Lehours P, Dubus P, et al.
PLoS Pathog 2021 Mar
Assessment of Atg7 and LC3II/LC3, as The Markers of Autophagy, in Sperm of Infertile Men with Globozoospermia: A Case-Control Study.
Foroozan-Boroojeni S, Tavalaee M, Zakeri Z, Lockshin RA, Nasr-Esfahani MH, et al.
Cell J 2021 Apr
The onco-immunological implications of Fusobacterium nucleatum in breast cancer.
Van der Merwe M, Van Niekerk G, Botha A, Engelbrecht AM
Immunol Lett 2021 Apr
YAP/TFEB pathway promotes autophagic cell death and hypertrophic cardiomyopathy in lysosomal storage diseases.
Rabinovich-Nikitin I, Kirshenbaum LA
J Clin Invest 2021 Mar 1
Ferroptosis and Photodynamic Therapy Synergism: Enhancing Anticancer Treatment.
Mishchenko TA, Balalaeva IV, Vedunova MV, Krysko DV
Trends Cancer 2021 Jun
Hydrogen gas inhalation alleviates myocardial ischemia-reperfusion injury by the inhibition of oxidative stress and NLRP3-mediated pyroptosis in rats.
Nie C, Ding X, A R, Zheng M, Li Z, et al.
Life Sci 2021 May 1
Immunostimulant hydrogel for the inhibition of malignant glioma relapse post-resection.
Zhang J, Chen C, Li A, Jing W, Sun P, et al.
Nat Nanotechnol 2021 May
Oxidized phosphatidylcholines trigger ferroptosis in cardiomyocytes during ischemia-reperfusion injury.
Stamenkovic A, O'Hara KA, Nelson DC, Maddaford TG, Edel AL, et al.
Am J Physiol Heart Circ Physiol 2021 Mar 1
Impact of different patterns of metastasis in non-small-cell lung cancer patients.
da Silva LM, da Silva GT, Bergmann A, Costa GJ, Zamboni MM, et al.
Future Oncol 2021 Mar
Cell-cycle risk score more accurately determines the risk for metastases and death in prostatectomy patients compared with clinical features alone.
Swanson GP, Lenz L, Stone S, Cohen T
Prostate 2021 Mar
NINJ1 mediates plasma membrane rupture during lytic cell death.
Kayagaki N, Kornfeld OS, Lee BL, Stowe IB, O'Rourke K, et al.
Nature 2021 Mar
Activation mechanisms of inflammasomes by bacterial toxins.
Jing W, Lo Pilato J, Kay C, Man SM
Cell Microbiol 2021 Apr
Acute chest syndrome in pediatric sickle cell disease: Associations with racial composition and neighborhood deprivation.
Alishlash AS, Rutland SB, Friedman AJ, Hampton JI, Nourani A, et al.
Pediatr Blood Cancer 2021 Apr
Compound XiongShao Capsule ameliorates streptozotocin-induced diabetic peripheral neuropathy in rats via inhibiting apoptosis, oxidative - nitrosative stress and advanced glycation end products.
Yu MX, Lei B, Song X, Huang YM, Ma XQ, et al.
J Ethnopharmacol 2021 Mar 25
Novel Ablation Therapy Using Endoscopic Irreversible Electroporation in the Bile Duct: A Pilot Animal Study.
Lee KW, Lee JM, Choi HS, Kim ES, Keum B, et al.
Clin Endosc 2021 May
Antioxidant functions of DHHC3 suppress anti-cancer drug activities.
Sharma C, Yang W, Steen H, Freeman MR, Hemler ME, et al.
Cell Mol Life Sci 2021 Mar
Non-lethal message from the Holy Land: The first international conference on nonapoptotic roles of apoptotic proteins.
Arama E, Baena-Lopez LA, Fearnhead HO
FEBS J 2021 Apr
MiR-647 promotes cisplatin-induced cell apoptosis via downregulating IGF2 in non-small cell lung cancer.
Jiang W, Zhao X, Yang W
Minerva Med 2021 Apr