Member Publications

HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy.
Strappazzon F, Di Rita A, Peschiaroli A, Leoncini PP, Locatelli F, et al.
Cell Death Differ 2019 Aug 21
Gedunin Degrades Aggregates of Mutant Huntingtin Protein and Intranuclear Inclusions via the Proteasomal Pathway in Neurons and Fibroblasts from Patients with Huntington's Disease.
Yang W, Xie J, Qiang Q, Li L, Lin X, et al.
Neurosci Bull 2019 Aug 20
Protopanaxadiol inhibits epithelial-mesenchymal transition of hepatocellular carcinoma by targeting STAT3 pathway.
Yang L, Zhang XY, Li K, Li AP, Yang WD, et al.
Cell Death Dis 2019 Aug 20
A flavone, Wogonin from Scutellaria baicalensis inhibits the proliferation of human colorectal cancer cells by inducing of autophagy, apoptosis and G2/M cell cycle arrest via modulating the PI3K/AKT and STAT3 signalling pathways.
Tan H, Li X, Yang WH, Kang Y
J BUON 2019 May-Jun
[Clinicopathological study of BCOR rearrangement in high grade endometrial stromal sarcoma].
Cheng YF, Bai QM, Bi R, Chang B, Huang D, et al.
Zhonghua Bing Li Xue Za Zhi 2019 Aug 8
Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β.
Talty A, Deegan S, Ljujic M, Mnich K, Naicker SD, et al.
Cell Death Dis 2019 Aug 16
Microglial-induced apoptosis is potentially responsible for hyperalgesia variations during CFA-induced inflammation.
Baniasadi M, Manaheji H, Maghsoudi N, Danyali S, Zakeri Z, et al.
Inflammopharmacology 2019 Aug 6
Tumor-treating fields induce autophagy by blocking the Akt2/miR29b axis in glioblastoma cells.
Kim EH, Jo Y, Sai S, Park MJ, Kim JY, et al.
Oncogene 2019 Aug 2
Maternal control of suspensor programmed cell death via gibberellin signaling.
Shi C, Luo P, Du YT, Chen H, Huang X, et al.
Nat Commun 2019 Aug 2
Mechanisms of doxorubicin-induced drug resistance and drug resistant tumour growth in a murine breast tumour model.
Christowitz C, Davis T, Isaacs A, van Niekerk G, Hattingh S, et al.
BMC Cancer 2019 Aug 1
ZBP1/DAI Drives RIPK3-Mediated Cell Death Induced by IFNs in the Absence of RIPK1.
Ingram JP, Thapa RJ, Fisher A, Tummers B, Zhang T, et al.
J Immunol 2019 Sep 1
Experimental Data-Mining Analyses Reveal New Roles of Low-Intensity Ultrasound in Differentiating Cell Death Regulatome in Cancer and Non-cancer Cells via Potential Modulation of Chromatin Long-Range Interactions.
Wang J, Lai B, Nanayakkara G, Yang Q, Sun Y, et al.
Front Oncol 2019
Thioredoxin inhibitor PX-12 induces mitochondria-mediated apoptosis in acute lymphoblastic leukemia cells.
Ehrenfeld V, Fulda S
Biol Chem 2019 Jul 29
Chloroplast-Localized Protoporphyrinogen IX Oxidase1 Is Involved in the Mitotic Cell Cycle in Arabidopsis.
Li J, Zhang F, Li Y, Yang W, Lin R, et al.
Plant Cell Physiol 2019 Jul 26
Hypoxia Modulates Effects of Fatty Acids on NES2Y Human Pancreatic β-cells.
Šrámek J, Němcová-Fürstová V, Polák J, Kovář J
Int J Mol Sci 2019 Jul 12
Oridonin enhances TRAIL-induced apoptosis through GALNT14-mediated DR5 glycosylation.
Jeon MY, Seo SU, Woo SM, Min KJ, Byun HS, et al.
Biochimie 2019 Jul 20
Norgestrel, a Progesterone Analogue, Promotes Significant Long-Term Neuroprotection of Cone Photoreceptors in a Mouse Model of Retinal Disease.
Roche SL, Kutsyr O, Cuenca N, Cotter TG
Invest Ophthalmol Vis Sci 2019 Jul 1
Autophagy: New Insights into Mechanisms of Action and Resistance of Treatment in Acute Promyelocytic leukemia.
Moosavi MA, Djavaheri-Mergny M
Int J Mol Sci 2019 Jul 20
Kinome screen of ferroptosis reveals a novel role of ATM in regulating iron metabolism.
Chen PH, Wu J, Ding CC, Lin CC, Pan S, et al.
Cell Death Differ 2019 Jul 18
NLRP3-dependent pyroptosis is required for HIV-1 gp120-induced neuropathology.
He X, Yang W, Zeng Z, Wei Y, Gao J, et al.
Cell Mol Immunol 2019 Jul 18
Multiple signaling pathways in Sertoli cells: recent findings in spermatogenesis.
Ni FD, Hao SL, Yang WX
Cell Death Dis 2019 Jul 17
IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion.
Chan LC, Li CW, Xia W, Hsu JM, Lee HH, et al.
J Clin Invest 2019 Jul 15
Rational application of the first-line chemotherapy and immune checkpoint inhibitors in advanced nonsmall cell lung cancer: A meta-analysis.
Cao R, Ma JT, Zhang SL, Sun L, Liu Y, et al.
Cancer Med 2019 Jul 11
Poly (rC) binding protein 2 interacts with VP0 and increases the replication of the foot-and-mouth disease virus.
Li D, Zhang J, Yang W, He Y, Ru Y, et al.
Cell Death Dis 2019 Jul 4
Axl Inhibitor R428 Enhances TRAIL-Mediated Apoptosis Through Downregulation of c-FLIP and Survivin Expression in Renal Carcinoma.
Woo SM, Min KJ, Seo SU, Kim S, Kubatka P, et al.
Int J Mol Sci 2019 Jul 2
Cardioprotective role of APIP in myocardial infarction through ADORA2B.
Lim B, Jung K, Gwon Y, Oh JG, Roh JI, et al.
Cell Death Dis 2019 Jul 1
Plasma receptor interacting protein kinase-3 levels are associated with acute respiratory distress syndrome in sepsis and trauma: a cohort study.
Shashaty MGS, Reilly JP, Faust HE, Forker CM, Ittner CAG, et al.
Crit Care 2019 Jun 28
Anticancer effect of fucoidan on cell proliferation, cell cycle progression, genetic damage and apoptotic cell death in HepG2 cancer cells.
P A, K A, L S, M M, K M, et al.
Toxicol Rep 2019
Herbal formula Yangyinjiedu induces lung cancer cell apoptosis via activation of early growth response 1.
Yang W, Kang Y, Zhao Q, Bi L, Jiao L, et al.
J Cell Mol Med 2019 Jun 25
Characterization of irreversible electroporation on the stomach: A feasibility study in rats.
Lee JM, Choi HS, Kim ES, Keum B, Seo YS, et al.
Sci Rep 2019 Jun 24
miR-211 facilitates platinum chemosensitivity by blocking the DNA damage response (DDR) in ovarian cancer.
Wang T, Hao D, Yang S, Ma J, Yang W, et al.
Cell Death Dis 2019 Jun 24
Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits.
Jung S, Choe S, Woo H, Jeong H, An HK, et al.
Autophagy 2019 Jun 24
Publisher Correction: Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.
Carreras-Sureda A, Jaña F, Urra H, Durand S, Mortenson DE, et al.
Nat Cell Biol 2019 Jul
RGD-containing elastin-like polypeptide improves islet transplantation outcomes in diabetic mice.
Lee KM, Kim JH, Choi ES, Kim E, Choi SK, et al.
Acta Biomater 2019 Aug
Autophagy-Independent Functions of the Autophagy Machinery.
Galluzzi L, Green DR
Cell 2019 Jun 13
Selective elimination of cancer cells by the adenovirus E4orf4 protein in a Drosophila cancer model: a new paradigm for cancer therapy.
Rosen H, Sharf R, Pechkovsky A, Salzberg A, Kleinberger T, et al.
Cell Death Dis 2019 Jun 11
Development of Theragnostic Tool Using NIR Fluorescence Probe Targeting Mitochondria in Glioma Cells.
Chu Y, Shin MC, Sung J, Park J, Kim E, et al.
Bioconjug Chem 2019 Jun 19
Staphylococcus aureus Orchestrates Type 2 Airway Diseases.
Teufelberger AR, Bröker BM, Krysko DV, Bachert C, Krysko O, et al.
Trends Mol Med 2019 Aug
Targeting ferroptosis in rhabdomyosarcoma cells.
Dächert J, Ehrenfeld V, Habermann K, Dolgikh N, Fulda S, et al.
Int J Cancer 2019 Jun 7
Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against Mycobacterium tuberculosis.
Kim EW, De Leon A, Jiang Z, Radu RA, Martineau AR, et al.
mSphere 2019 Jun 5
Combined effect of alpha particles and cigarette smoke on human lung epithelial cells <i>in vitro</i>.
Lee US, Kim EH
Int J Radiat Biol 2019 Jun 12
Ubiquitin Ligases cIAP1 and cIAP2 Limit Cell Death to Prevent Inflammation.
Zhang J, Webster JD, Dugger DL, Goncharov T, Roose-Girma M, et al.
Cell Rep 2019 May 28
Kinesin-14 motor protein KIFC1 participates in DNA synthesis and chromatin maintenance.
Wei YL, Yang WX
Cell Death Dis 2019 May 24
Concomitant targeting of BCL2 with venetoclax and MAPK signaling with cobimetinib in acute myeloid leukemia models.
Han L, Zhang Q, Dail M, Shi C, Cavazos A, et al.
Haematologica 2019 May 23
Mitophagy in Cancer: A Tale of Adaptation.
Vara-Perez M, Felipe-Abrio B, Agostinis P
Cells 2019 May 22
The paracrine effects of fibroblasts on Doxorubicin-treated breast cancer cells.
Fourie C, Davis T, Kriel J, Engelbrecht AM
Exp Cell Res 2019 Aug 15
IRF2 transcriptionally induces <i>GSDMD</i> expression for pyroptosis.
Kayagaki N, Lee BL, Stowe IB, Kornfeld OS, O'Rourke K, et al.
Sci Signal 2019 May 21
Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.
Carreras-Sureda A, Jaña F, Urra H, Durand S, Mortenson DE, et al.
Nat Cell Biol 2019 Jun
Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion.
Friedmann Angeli JP, Krysko DV, Conrad M
Nat Rev Cancer 2019 Jul
The Coming Decade of Cell Death Research: Five Riddles.
Green DR
Cell 2019 May 16
Risk of dermatologic and mucosal adverse events associated with PD-1/PD-L1 inhibitors in cancer patients: A meta-analysis of randomized controlled trials.
Yang W, Li S, Yang Q
Medicine (Baltimore) 2019 May
Involvement of TREK-1 Channel in Cell Viability of H9c2 Rat Cardiomyoblasts Affected by Bupivacaine and Lipid Emulsion.
Yang JH, Siregar AS, Kim EJ, Nyiramana MM, Shin EJ, et al.
Cells 2019 May 14
PD-L1 expression and tumor mutational burden status for prediction of response to chemotherapy and targeted therapy in non-small cell lung cancer.
Chen Y, Liu Q, Chen Z, Wang Y, Yang W, et al.
J Exp Clin Cancer Res 2019 May 14
Transcriptomic Analysis Reveals a Comprehensive Calcium- and Phytohormone-Dominated Signaling Response in <i>Leymus chinensis</i> Self-Incompatibility.
Chen S, Jia J, Cheng L, Zhao P, Qi D, et al.
Int J Mol Sci 2019 May 13
EMT is the major target for okadaic acid-suppressed the development of neural crest cells in chick embryo.
Jiao YH, Liu M, Wang G, Li HY, Liu JS, et al.
Ecotoxicol Environ Saf 2019 Sep 30
Targeting monocyte-intrinsic enhancer reprogramming improves immunotherapy efficacy in hepatocellular carcinoma.
Liu M, Zhou J, Liu X, Feng Y, Yang W, et al.
Gut 2019 May 10
Redox (phospho)lipidomics of signaling in inflammation and programmed cell death.
Tyurina YY, St Croix CM, Watkins SC, Watson AM, Epperly MW, et al.
J Leukoc Biol 2019 Jul
nNOS/GSNOR interaction contributes to skeletal muscle differentiation and homeostasis.
Montagna C, Rizza S, Cirotti C, Maiani E, Muscaritoli M, et al.
Cell Death Dis 2019 May 1
A new split-luciferase complementation assay identifies pentachlorophenol as an inhibitor of apoptosome formation.
Tashakor A, H-Dehkordi M, O'Connell E, Gomez Ganau S, Gozalbes R, et al.
FEBS Open Bio 2019 Jul
Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites.
McNamara DE, Dovey CM, Hale AT, Quarato G, Grace CR, et al.
Cell Chem Biol 2019 Jun 20
Immunogenic neoantigens derived from gene fusions stimulate T cell responses.
Yang W, Lee KW, Srivastava RM, Kuo F, Krishna C, et al.
Nat Med 2019 May
Discovery of SCY45, a Natural Small-Molecule MDM2-p53 Interaction Inhibitor.
Gong H, An J, Dong Q, Li J, Yang W, et al.
Chem Biodivers 2019 Jun
DR4-Ser424 <i>O</i>-GlcNAcylation Promotes Sensitization of TRAIL-Tolerant Persisters and TRAIL-Resistant Cancer Cells to Death.
Lee H, Oh Y, Jeon YJ, Lee SY, Kim H, et al.
Cancer Res 2019 Jun 1
Autophagy as a molecular target for cancer treatment.
Kocaturk NM, Akkoc Y, Kig C, Bayraktar O, Gozuacik D, et al.
Eur J Pharm Sci 2019 Jun 15
NEAT1 promotes myocardial ischemia-reperfusion injury via activating the MAPK signaling pathway.
Du XJ, Wei J, Tian D, Yan C, Hu P, et al.
J Cell Physiol 2019 Aug
A polysaccharide from dried aerial parts of Agrimonia pilosa: Structural characterization and its potential therapeutic activity for steroid‑induced necrosis of the femoral head (SANFH).
Huang W, Deng H, Jin S, Yang W, Wang H, et al.
Carbohydr Polym 2019 Jun 15
PERK regulates Nrf2/ARE antioxidant pathway against dibutyl phthalate-induced mitochondrial damage and apoptosis dependent of reactive oxygen species in mouse spermatocyte-derived cells.
Zhang G, Yang W, Jiang F, Zou P, Zeng Y, et al.
Toxicol Lett 2019 Jun 15
Controlling metastatic cancer: the role of phytochemicals in cell signaling.
Kapinova A, Kubatka P, Liskova A, Baranenko D, Kruzliak P, et al.
J Cancer Res Clin Oncol 2019 May
Captopril attenuates TAC-induced heart failure via inhibiting Wnt3a/β-catenin and Jak2/Stat3 pathways.
Zhang Y, Zhang L, Fan X, Yang W, Yu B, et al.
Biomed Pharmacother 2019 May
Morin enhances auranofin anticancer activity by up-regulation of DR4 and DR5 and modulation of Bcl-2 through reactive oxygen species generation in Hep3B human hepatocellular carcinoma cells.
Hwang-Bo H, Lee WS, Nagappan A, Kim HJ, Panchanathan R, et al.
Phytother Res 2019 May
Korean Red ginseng extract inhibits glioblastoma propagation by blocking the Wnt signaling pathway.
Ham SW, Kim JK, Jeon HY, Kim EJ, Jin X, et al.
J Ethnopharmacol 2019 May 23
β-Apopicropodophyllin functions as a radiosensitizer targeting ER stress in non-small cell lung cancer.
Kim JY, Cho JH, Kim EM, Shin HJ, Hwang SG, et al.
Biomed Pharmacother 2019 May
MERTK tyrosine kinase receptor together with TIM4 phosphatidylserine receptor mediates distinct signal transduction pathways for efferocytosis and cell proliferation.
Nishi C, Yanagihashi Y, Segawa K, Nagata S
J Biol Chem 2019 May 3
Cathepsins: Potent regulators in carcinogenesis.
Khaket TP, Kwon TK, Kang SC
Pharmacol Ther 2019 Jun
TAZ stimulates liver regeneration through interleukin-6-induced hepatocyte proliferation and inhibition of cell death after liver injury.
Kim AR, Park JI, Oh HT, Kim KM, Hwang JH, et al.
FASEB J 2019 May
Stearate-Induced Apoptosis in Human Pancreatic β-Cells is Associated with Changes in Membrane Protein Expression and These Changes are Inhibited by Oleate.
Němcová-Fürstová V, Balušíková K, Halada P, Pavlíková N, Šrámek J, et al.
Proteomics Clin Appl 2019 Jul
Noncoding RNAs regulating cardiac muscle mass.
Wadley GD, Lamon S, Alexander SE, McMullen JR, Bernardo BC, et al.
J Appl Physiol (1985) 2019 Aug 1
Casticin inhibits growth and enhances ionizing radiation-induced apoptosis through the suppression of STAT3 signaling cascade.
Lee JH, Kim C, Ko JH, Jung YY, Jung SH, et al.
J Cell Biochem 2019 Jun
Phosphoprotein patterns predict trametinib responsiveness and optimal trametinib sensitisation strategies in melanoma.
Rožanc J, Sakellaropoulos T, Antoranz A, Guttà C, Podder B, et al.
Cell Death Differ 2019 Aug
Caveolin-1 impairs PKA-DRP1-mediated remodelling of ER-mitochondria communication during the early phase of ER stress.
Bravo-Sagua R, Parra V, Ortiz-Sandoval C, Navarro-Marquez M, Rodríguez AE, et al.
Cell Death Differ 2019 Jul
Loss of receptor interacting protein kinases 3 and caspase-8 augments intrinsic apoptosis in tubular epithelial cell and promote kidney ischaemia-reperfusion injury.
Sung B, Su Y, Jiang J, Mcleod P, Liu W, et al.
Nephrology (Carlton) 2019 Jun
Clinical significance of isoagglutinin titre with the current desensitization protocol in ABO-incompatible kidney transplantation.
Baek CH, Kim H, Yang WS, Han DJ, Park SK, et al.
Nephrology (Carlton) 2019 Jun
Remote organ failure in acute kidney injury.
Kao CC, Yang WS, Fang JT, Liu KD, Wu VC, et al.
J Formos Med Assoc 2019 May