Member Publications

DR4-Ser424 O-GlcNAcylation promotes sensitization of TRAIL-tolerant persisters and TRAIL-resistant cancer cells to death.
Lee H, Oh Y, Jeon YJ, Lee SY, Kim H, et al.
Cancer Res 2019 Apr 15

NSC-34 motor neuron-like cells are sensitized to ferroptosis upon differentiation.
Martinez AM, Mirkovic J, Stanisz ZA, Patwari FS, Yang WS, et al.
FEBS Open Bio 2019 Apr

The ARTS of Cell Death.
Koren E, Fuchs Y
J Cell Death 2019

Autophagy as a molecular target for cancer treatment.
Kocaturk NM, Akkoc Y, Kig C, Bayraktar O, Gozuacik D, et al.
Eur J Pharm Sci 2019 Apr 11

Minocycline mitigates the effect of neonatal hypoxic insult on human brain organoids.
Boisvert EM, Means RE, Michaud M, Madri JA, Katz SG, et al.
Cell Death Dis 2019 Apr 11

NEAT1 promotes myocardial ischemia-reperfusion injury via activating the MAPK signaling pathway.
Du XJ, Wei J, Tian D, Yan C, Hu P, et al.
J Cell Physiol 2019 Apr 4

Lysosomal Pathways and Autophagy Distinctively Control Endothelial Cell Behavior to Affect Tumor Vasculature.
Schaaf MB, Houbaert D, Meçe O, To SK, Ganne M, et al.
Front Oncol 2019

Reversible induction of mitophagy by an optogenetic bimodular system.
D'Acunzo P, Strappazzon F, Caruana I, Meneghetti G, Di Rita A, et al.
Nat Commun 2019 Apr 4

The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors.
Mahameed M, Wilhelm T, Darawshi O, Obiedat A, Tommy WS, et al.
Cell Death Dis 2019 Apr 1

The role of lncRNA MSC-AS1/miR-29b-3p axis-mediated CDK14 modulation in pancreatic cancer proliferation and Gemcitabine-induced apoptosis.
Sun Y, Wang P, Yang W, Shan Y, Zhang Q, et al.
Cancer Biol Ther 2019 Mar 27

Structure and Neuroprotective Effect of Polysaccharide from Viscera Autolysates of Squid <i>Ommastrephes bartrami</i>.
Ye P, Li P, Yang W, Zhao Y, Zhao Y, et al.
Mar Drugs 2019 Mar 22

Controlling metastatic cancer: the role of phytochemicals in cell signaling.
Kapinova A, Kubatka P, Liskova A, Baranenko D, Kruzliak P, et al.
J Cancer Res Clin Oncol 2019 Mar 22

Mitochondrial origins of fractional control in regulated cell death.
Santos LC, Vogel R, Chipuk JE, Birtwistle MR, Stolovitzky G, et al.
Nat Commun 2019 Mar 21

Elevated FPR confers to radiochemoresistance and predicts clinical efficacy and outcome of metastatic colorectal cancer patients.
Chen QG, Zhang L, Sun F, Li SQ, You XH, et al.
Aging (Albany NY) 2019 Mar 21

Protease/antiprotease network in allergy: The role of Staphylococcus aureus protease-like proteins.
Krysko O, Teufelberger A, Van Nevel S, Krysko DV, Bachert C, et al.
Allergy 2019 Mar 19

Morin enhances auranofin anticancer activity by up-regulation of DR4 and DR5 and modulation of Bcl-2 through reactive oxygen species generation in Hep3B human hepatocellular carcinoma cells.
Hwang-Bo H, Lee WS, Nagappan A, Kim HJ, Panchanathan R, et al.
Phytother Res 2019 Mar 19

Korean Red ginseng extract inhibits glioblastoma propagation by blocking the Wnt signaling pathway.
Ham SW, Kim JK, Jeon HY, Kim EJ, Jin X, et al.
J Ethnopharmacol 2019 May 23

β-Apopicropodophyllin functions as a radiosensitizer targeting ER stress in non-small cell lung cancer.
Kim JY, Cho JH, Kim EM, Shin HJ, Hwang SG, et al.
Biomed Pharmacother 2019 May

Targeting Epidermal Growth Factor Receptor in Non-Small-Cell-Lung Cancer: Current State and Future Perspective.
Bao SM, Hu QH, Yang WT, Wang Y, Tong YP, et al.
Anticancer Agents Med Chem 2019 Mar 13

Combination immunotherapy with IL-4 Pseudomonas exotoxin and IFN-α and IFN-γ mediate antitumor effects in vitro and in a mouse model of human ovarian cancer.
Green DS, Husain SR, Johnson CL, Sato Y, Han J, et al.
Immunotherapy 2019 Apr

Bafilomycin-A1 and ML9 exert different lysosomal actions to induce cell death.
Shaikh S, Nandy SK, Canti C, Lavandero S
Curr Mol Pharmacol 2019 Mar 8

A Novel Lactate Dehydrogenase Inhibitor, 1-(Phenylseleno)-4-(Trifluoromethyl) Benzene, Suppresses Tumor Growth through Apoptotic Cell Death.
Kim EY, Chung TW, Han CW, Park SY, Park KH, et al.
Sci Rep 2019 Mar 8

MERTK tyrosine kinase receptor together with TIM4 phosphatidylserine receptor mediates distinct signal transduction pathways for efferocytosis and cell proliferation.
Nishi C, Yanagihashi Y, Segawa K, Nagata S
J Biol Chem 2019 Mar 7

IL-1β and TNFα Differentially Influence NF-κB Activity and FasL-Induced Apoptosis in Primary Murine Hepatocytes During LPS-Induced Inflammation.
Rex J, Lutz A, Faletti LE, Albrecht U, Thomas M, et al.
Front Physiol 2019

ABHD5 blunts the sensitivity of colorectal cancer to fluorouracil via promoting autophagic uracil yield.
Ou J, Peng Y, Yang W, Zhang Y, Hao J, et al.
Nat Commun 2019 Mar 6

Pro-apoptotic and pro-proliferation functions of the JNK pathway of Drosophila: roles in cell competition, tumorigenesis and regeneration.
Pinal N, Calleja M, Morata G
Open Biol 2019 Mar 29

In Situ Dendritic Cell Vaccine for Effective Cancer Immunotherapy.
Yang W, Zhu G, Wang S, Yu G, Yang Z, et al.
ACS Nano 2019 Mar 26

Inhibition of lymphatic proliferation by the selective VEGFR-3 inhibitor SAR131675 ameliorates diabetic nephropathy in db/db mice.
Hwang SD, Song JH, Kim Y, Lim JH, Kim MY, et al.
Cell Death Dis 2019 Mar 4

Sortilin promotes glioblastoma invasion and mesenchymal transition through GSK-3β/β-catenin/twist pathway.
Yang W, Wu PF, Ma JX, Liao MJ, Wang XH, et al.
Cell Death Dis 2019 Feb 27

Autophagy is Required to Regulate Mitochondria Renewal, Cell Attachment, and All-trans-Retinoic Acid-Induced Differentiation in NB4 Acute Promyelocytic Leukemia Cells.
Tekedereli I, Akar U, Alpay SN, Lopez-Berestein G, Ozpolat B, et al.
J Environ Pathol Toxicol Oncol 2019

Epidermal Growth Factor Receptor-Targeted Multifunctional Photosensitizers for Bladder Cancer Imaging and Photodynamic Therapy.
Cheruku RR, Cacaccio J, Durrani FA, Tabaczynski WA, Watson R, et al.
J Med Chem 2019 Mar 14

Smac mimetic suppresses tunicamycin-induced apoptosis via resolution of ER stress.
Abhari BA, McCarthy N, Le Berre M, Kilcoyne M, Joshi L, et al.
Cell Death Dis 2019 Feb 15

PLOD3 suppression exerts an anti-tumor effect on human lung cancer cells by modulating the PKC-delta signaling pathway.
Baek JH, Yun HS, Kwon GT, Lee J, Kim JY, et al.
Cell Death Dis 2019 Feb 15

Cytochrome <i>c</i> Deficiency Confers Apoptosome and Mitochondrial Dysfunction in African-American Men with Prostate Cancer.
Kumar R, Bhat TA, Walsh EM, Chaudhary AK, O'Malley J, et al.
Cancer Res 2019 Apr 1

Cathepsins: Potent regulators in carcinogenesis.
Khaket TP, Kwon TK, Kang SC
Pharmacol Ther 2019 Feb 11

Modulation of the ATM/autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells.
Beauvarlet J, Bensadoun P, Darbo E, Labrunie G, Rousseau B, et al.
Nucleic Acids Res 2019 Apr 8

Stanniocalcin‑1 promotes cell proliferation, chemoresistance and metastasis in hypoxic gastric cancer cells via Bcl‑2.
Wang Y, Qi Z, Zhou M, Yang W, Hu R, et al.
Oncol Rep 2019 Mar

Endoplasmic reticulum stress and NLRP3 inflammasome: Crosstalk in cardiovascular and metabolic disorders.
Ji T, Han Y, Yang W, Xu B, Sun M, et al.
J Cell Physiol 2019 Feb 11

TAZ stimulates liver regeneration through interleukin-6-induced hepatocyte proliferation and inhibition of cell death after liver injury.
Kim AR, Park JI, Oh HT, Kim KM, Hwang JH, et al.
FASEB J 2019 Feb 11

Circadian-Regulated Cell Death in Cardiovascular Diseases.
Rabinovich-Nikitin I, Lieberman B, Martino TA, Kirshenbaum LA
Circulation 2019 Feb 12

Cell cycle arrest in mitosis promotes interferon-induced necroptosis.
Frank T, Tuppi M, Hugle M, Dötsch V, van Wijk SJL, et al.
Cell Death Differ 2019 Feb 11

Author Correction: Caveolin-1 impairs PKA-DRP1-mediated remodelling of ER-mitochondria communication during the early phase of ER stress.
Bravo-Sagua R, Parra V, Ortiz-Sandoval C, Navarro-Marquez M, Rodríguez AE, et al.
Cell Death Differ 2019 Feb 11

Interview: a conversation with Vishva M Dixit on his journey from remote African village to apoptosis, necroptosis and the inflammasome.
Dixit VM
Cell Death Differ 2019 Mar

Staying in touch: Taking a closer look at ER-Golgi contact sites.
Sassano ML, Agostinis P
J Cell Biol 2019 Mar 4

Cationic amino acid transporter PQLC2 is a potential therapeutic target in gastric cancer.
Jeung YJ, Lee K, Lee HJ, Kim E, Son MJ, et al.
Cancer Sci 2019 Apr

Pilose Antler Extracts (PAEs) Protect against Neurodegeneration in 6-OHDA-Induced Parkinson's Disease Rat Models.
Li C, Sun Y, Yang W, Ma S, Zhang L, et al.
Evid Based Complement Alternat Med 2019

Autophagy and cancer stem cells: molecular mechanisms and therapeutic applications.
Nazio F, Bordi M, Cianfanelli V, Locatelli F, Cecconi F, et al.
Cell Death Differ 2019 Mar

Autophagy in endothelial cells and tumor angiogenesis.
Schaaf MB, Houbaert D, Meçe O, Agostinis P
Cell Death Differ 2019 Mar

NF-κB contributes to Smac mimetic-conferred protection from tunicamycin-induced apoptosis.
Abhari BA, McCarthy N, Agostinis P, Fulda S
Apoptosis 2019 Jan 24

Stearate-Induced Apoptosis in Human Pancreatic β-Cells is Associated with Changes in Membrane Protein Expression and These Changes are Inhibited by Oleate.
Němcová-Fürstová V, Balušíková K, Halada P, Pavlíková N, Šrámek J, et al.
Proteomics Clin Appl 2019 Jan 21

Targeting intrinsic cell death pathways to control fungal pathogens.
Kulkarni M, Stolp ZD, Hardwick JM
Biochem Pharmacol 2019 Apr

Immune Checkpoint Inhibitor-induced Reinvigoration of Tumor-infiltrating CD8⁺ T Cells is Determined by Their Differentiation Status in Glioblastoma.
Park J, Kwon M, Kim KH, Kim TS, Hong SH, et al.
Clin Cancer Res 2019 Apr 15

Cotreatment with sorafenib and oleanolic acid induces reactive oxygen species-dependent and mitochondrial-mediated apoptotic cell death in hepatocellular carcinoma cells.
Liese J, Hinrichs TM, Lange M, Fulda S
Anticancer Drugs 2019 Mar

Human Leukocyte Antigen Class I and Programmed Death-Ligand 1 Coexpression Is an Independent Poor Prognostic Factor in Adenocarcinoma of the Lung.
Han YB, Kwon HJ, Park SY, Kim ES, Kim H, et al.
J Pathol Transl Med 2019 Mar

Paroxetine Induces Apoptosis of Human Breast Cancer MCF-7 Cells through Ca²⁺-and p38 MAP Kinase-Dependent ROS Generation.
Cho YW, Kim EJ, Nyiramana MM, Shin EJ, Jin H, et al.
Cancers (Basel) 2019 Jan 9

Bone metastases and skeletal-related events: incidence and prognosis according to histological subtype of lung cancer.
Silva GT, Silva LM, Bergmann A, Thuler LC
Future Oncol 2019 Feb

Accurate elimination of superfluous attachment cells is critical for the construction of functional multicellular proprioceptors in Drosophila.
Avetisyan A, Salzberg A
Cell Death Differ 2019 Jan 8

Preclinical pharmacodynamic evaluation of a new Src/FOSL1 inhibitor, LY-1816, in pancreatic ductal adenocarcinoma.
Yang W, Meng L, Chen K, Tian C, Peng B, et al.
Cancer Sci 2019 Apr

The Cell-Death-Associated Polymer PAR Feeds Forward α-Synuclein Toxicity in Parkinson's Disease.
Donyo M, Ashkenazi A
Mol Cell 2019 Jan 3

JAK2 regulation by licochalcone H inhibits the cell growth and induces apoptosis in oral squamous cell carcinoma.
Oh HN, Oh KB, Lee MH, Seo JH, Kim E, et al.
Phytomedicine 2019 Jan

PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndrome.
Spinazzi M, Radaelli E, Horré K, Arranz AM, Gounko NV, et al.
Proc Natl Acad Sci U S A 2019 Jan 2

Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma.
Ma H, Yang W, Zhang L, Liu S, Zhao M, et al.
Br J Cancer 2019 Feb

LncRNA KTN1-AS1 promotes tumor growth of hepatocellular carcinoma by targeting miR-23c/ERBB2IP axis.
Zhang L, Wang L, Wang Y, Chen T, Liu R, et al.
Biomed Pharmacother 2019 Jan

Programmed death ligand-1 is associated with tumor infiltrating lymphocytes and poorer survival in urothelial cell carcinoma of the bladder.
Wang B, Pan W, Yang M, Yang W, He W, et al.
Cancer Sci 2019 Feb

Amelioration of amyloid β-FcγRIIb neurotoxicity and tau pathologies by targeting LYN.
Gwon Y, Kim SH, Kim HT, Kam TI, Park J, et al.
FASEB J 2019 Mar

Overview of BCL-2 Family Proteins and Therapeutic Potentials.
Huska JD, Lamb HM, Hardwick JM
Methods Mol Biol 2019

Bioaccumulation of polystyrene nanoplastics and their effect on the toxicity of Au ions in zebrafish embryos.
Lee WS, Cho HJ, Kim E, Huh YH, Kim HJ, et al.
Nanoscale 2019 Feb 14

An emerging role for nanomaterials in increasing immunogenicity of cancer cell death.
Mishchenko T, Mitroshina E, Balalaeva I, Krysko O, Vedunova M, et al.
Biochim Biophys Acta Rev Cancer 2019 Jan

Interferons Transcriptionally Up-Regulate MLKL Expression in Cancer Cells.
Knuth AK, Rösler S, Schenk B, Kowald L, van Wijk SJL, et al.
Neoplasia 2019 Jan

To the edge of cell death and back.
Gong YN, Crawford JC, Heckmann BL, Green DR
FEBS J 2019 Feb

Up-regulation of P-gp via NF-κB activation confers protection against oxidative damage in the retinal pigment epithelium cells.
Feng Q, Yang W, Gao Z, Ruan X, Zhang Y, et al.
Exp Eye Res 2019 Apr

Gene Therapy in Head and Neck Cancer.
Farmer ZL, Kim ES, Carrizosa DR
Oral Maxillofac Surg Clin North Am 2019 Feb

Differential involvement of TAK1, RIPK1 and NF-κB signaling in Smac mimetic-induced cell death in breast cancer cells.
Schmidt N, Kowald L, van Wijk SJL, Fulda S
Biol Chem 2019 Jan 28

EUS-guided irreversible electroporation using endoscopic needle-electrode in porcine pancreas.
Lee JM, Choi HS, Chun HJ, Kim ES, Keum B, et al.
Surg Endosc 2019 Feb

Knockdown of PSMC3IP suppresses the proliferation and xenografted tumorigenesis of hepatocellular carcinoma cell.
Ding J, Li Y, Fan H, Xu W, Gao R, et al.
J Cell Biochem 2019 Apr

Comparison of main molecular markers involved in autophagy and apoptosis pathways between spermatozoa of infertile men with varicocele and fertile individuals.
Foroozan-Broojeni S, Tavalaee M, Lockshin RA, Zakeri Z, Abbasi H, et al.
Andrologia 2019 Mar

Programmed Necrosis and Disease:We interrupt your regular programming to bring you necroinflammation.
Kim EH, Wong SW, Martinez J
Cell Death Differ 2019 Jan

Crashing the computer: apoptosis vs. necroptosis in neuroinflammation.
Heckmann BL, Tummers B, Green DR
Cell Death Differ 2019 Jan

Cell Death Analysis in Retinal Cultures.
Roche SL, Ruiz-Lopez AM, Cotter TG
Methods Mol Biol 2019

Reciprocal regulations between miRNAs and HIF-1α in human cancers.
Yang W, Ma J, Zhou W, Cao B, Zhou X, et al.
Cell Mol Life Sci 2019 Feb

MicroRNA-645 represses hepatocellular carcinoma progression by inhibiting SOX30-mediated p53 transcriptional activation.
Tao J, Liu Z, Wang Y, Wang L, Yin G, et al.
Int J Biol Macromol 2019 Jan

About canonical, non-canonical and immunogenic cell death: Basic mechanisms and translational applications: A meeting report of the International Cell Death Society.
Zakeri Z, Lockshin RA, Diederich M
Biochem Pharmacol 2019 Apr

Renal dysfunction is rare in Fukuyama congenital muscular dystrophy.
Ishigaki K, Kato I, Murakami T, Sato T, Shichiji M, et al.
Brain Dev 2019 Jan

Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications.
Almanza A, Carlesso A, Chintha C, Creedican S, Doultsinos D, et al.
FEBS J 2019 Jan

BNIP3 contributes to the glutamine-driven aggressive behavior of melanoma cells.
Vara-Perez M, Maes H, Van Dingenen S, Agostinis P
Biol Chem 2019 Jan 28

Reduction of myocardial ischaemia-reperfusion injury by inactivating oxidized phospholipids.
Yeang C, Hasanally D, Que X, Hung MY, Stamenkovic A, et al.
Cardiovasc Res 2019 Jan 1

TP53 gain-of-function mutation promotes inflammation in glioblastoma.
Ham SW, Jeon HY, Jin X, Kim EJ, Kim JK, et al.
Cell Death Differ 2019 Mar

Changes in interleukin-10 and apoptotic genes in rats with myocardial infarction.
Yang W, Zhao Y, Liu N, Cao X, Xing C, et al.
Minerva Med 2019 Feb