Member Publications

TRAIL-induced variation of cell signaling states provides nonheritable resistance to apoptosis.
Baskar R, Fienberg HG, Khair Z, Favaro P, Kimmey S, et al.
Life Sci Alliance 2019 Dec

Bypassing pro-survival and resistance mechanisms of autophagy in EGFR-positive lung cancer cells by targeted delivery of 5FU using theranostic Ag2S quantum dots.
Duman FD, Akkoc Y, Demirci G, Bavili N, Kiraz A, et al.
J Mater Chem B 2019 Nov 7

AKT1-targeted proapoptotic activity of compound K in human breast cancer cells.
Choi E, Kim E, Kim JH, Yoon K, Kim S, et al.
J Ginseng Res 2019 Oct

ASPP2 inhibits tumor growth by repressing the mevalonate pathway in hepatocellular carcinoma.
Liang B, Chen R, Song S, Wang H, Sun G, et al.
Cell Death Dis 2019 Nov 4

Nanocomposite packaging regulates extracellular ATP and programed cell death in edible mushroom (Flammulina velutipes).
Shi C, Wu Y, Fang D, Ma N, Mariga AM, et al.
Food Chem 2019 Oct 19

Molecular insights on cytochrome c and nucleotide regulation of apoptosome function and its implication in cancer.
Yadav N, Gogada R, O'Malley J, Gundampati RK, Jayanthi S, et al.
Biochim Biophys Acta Mol Cell Res 2019 Oct 31

A matter of life and death: Molecular, physiological, and environmental regulation of seed longevity.
Zhou W, Chen F, Luo X, Dai Y, Yang Y, et al.
Plant Cell Environ 2019 Nov 1

Correction to: HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy.
Strappazzon F, Di Rita A, Peschiaroli A, Leoncini PP, Locatelli F, et al.
Cell Death Differ 2019 Oct 30

Destined to Die: Apoptosis and Pediatric Cancers.
Choo Z, Loh AHP, Chen ZX
Cancers (Basel) 2019 Oct 23

A TAZ-ANGPTL4-NOX2 Axis Regulates Ferroptotic Cell Death and Chemoresistance in Epithelial Ovarian Cancer.
Yang WH, Huang Z, Wu J, Ding CC, Murphy SK, et al.
Mol Cancer Res 2019 Oct 22

The requirement of SUMO2/3 for SENP2 mediated extraembryonic and embryonic development.
Yu HI, Hsu T, Maruyama EO, Paschen W, Yang W, et al.
Dev Dyn 2019 Oct 17

Involvement of Up-regulation of Death Receptors and Bim in Hispolon-mediated TNF-related Apoptosis-inducing Ligand Sensitization in Human Renal Carcinoma.
Yun JM, Min KJ, Kwon TK
J Cancer Prev 2019 Sep

Effect of novel porphyrazine photosensitizers on normal and tumor brain cells.
Mishchenko TA, Turubanova VD, Mitroshina EV, Alzeibak R, Peskova NN, et al.
J Biophotonics 2019 Oct 8

[Outcome of children with T cell acute lymphoblastic leukemia treated with Chinese Children Leukemia Group acute lymphoblastic leukemia (CCLG-ALL) 2008 protocol].
Liu XM, Chen XJ, Zou Y, Wang SC, Wang M, et al.
Zhonghua Er Ke Za Zhi 2019 Oct 2

Emerging role of mitophagy in cardiovascular physiology and pathology.
Morales PE, Arias-Durán C, Ávalos-Guajardo Y, Aedo G, Verdejo HE, et al.
Mol Aspects Med 2019 Oct 3

LanCL1 promotes motor neuron survival and extends the lifespan of amyotrophic lateral sclerosis mice.
Tan H, Chen M, Pang D, Xia X, Du C, et al.
Cell Death Differ 2019 Sep 30

Calreticulin is a Critical Cell Survival Factor in Malignant Neoplasms.
Han A, Li C, Zahed T, Wong M, Smith I, et al.
PLoS Biol 2019 Sep

Impaired NF-κB signalling underlies cyclophilin D-mediated mitochondrial permeability transition pore opening in doxorubicin cardiomyopathy.
Dhingra R, Guberman M, Rabinovich-Nikitin I, Gerstein J, Margulets V, et al.
Cardiovasc Res 2019 Sep 6

Single-Cell and Population-Level Analyses Using Real-Time Kinetic Labeling Couples Proliferation and Cell Death Mechanisms.
Gelles JD, Mohammed JN, Santos LC, Legarda D, Ting AT, et al.
Dev Cell 2019 Oct 21

Comparative analysis of urban road dust compositions in relation to their potential human health impacts.
Koh B, Kim EA
Environ Pollut 2019 Dec

Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells.
Pataer A, Ozpolat B, Shao R, Cashman NR, Plotkin SS, et al.
Oncogene 2019 Sep 25

Cellular Stress Responses in Radiotherapy.
Kim W, Lee S, Seo D, Kim D, Kim K, et al.
Cells 2019 Sep 18

The Dark Side of Estrogen Stops Translation to Induce Apoptosis.
Lamb HM, Hardwick JM
Mol Cell 2019 Sep 19

Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites.
Holdgaard SG, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, et al.
Nat Commun 2019 Sep 13

Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis.
Newton K, Wickliffe KE, Dugger DL, Maltzman A, Roose-Girma M, et al.
Nature 2019 Oct

Applied electric fields suppress osimertinib-induced cytotoxicity via inhibiting FOXO3a nuclear translocation through AKT activation.
Li L, Hu C, Lu C, Zhang K, Han R, et al.
Carcinogenesis 2019 Aug 31

Extracellular vesicles in vascular calcification.
Yang W, Zou B, Hou Y, Yan W, Chen T, et al.
Clin Chim Acta 2019 Dec

Mitochondrial E3 ubiquitin ligase 1 promotes autophagy flux to suppress the development of clear cell renal cell carcinomas.
Yuan Y, Li X, Xu Y, Zhao H, Su Z, et al.
Cancer Sci 2019 Nov

The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma.
Yang WH, Ding CC, Sun T, Rupprecht G, Lin CC, et al.
Cell Rep 2019 Sep 3

Ginsenoside Compound K Induces Ros-Mediated Apoptosis and Autophagic Inhibition in Human Neuroblastoma Cells In Vitro and In Vivo.
Oh JM, Kim E, Chun S
Int J Mol Sci 2019 Sep 1

Concomitant targeting of Hedgehog signaling and MCL-1 synergistically induces cell death in Hedgehog-driven cancer cells.
Meister MT, Boedicker C, Linder B, Kögel D, Klingebiel T, et al.
Cancer Lett 2019 Nov 28

RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity.
Orozco SL, Daniels BP, Yatim N, Messmer MN, Quarato G, et al.
Cell Rep 2019 Aug 27

Palmitic Acid-Rich High Fat Diet Exacerbates Experimental Pulmonary Fibrosis by Modulating Endoplasmic Reticulum Stress.
Chu SG, Villalba JA, Liang X, Xiong K, Tsoyi K, et al.
Am J Respir Cell Mol Biol 2019 Aug 28

Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress.
Shemorry A, Harnoss JM, Guttman O, Marsters SA, Kőműves LG, et al.
Elife 2019 Aug 27

Pachypodol, a Methoxyflavonoid Isolated from Pogostemon cablin Bentham Exerts Antioxidant and Cytoprotective Effects in HepG2 Cells: Possible Role of ERK-Dependent Nrf2 Activation.
Kim EK, Kim JH, Jeong S, Choi YW, Choi HJ, et al.
Int J Mol Sci 2019 Aug 21

HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy.
Strappazzon F, Di Rita A, Peschiaroli A, Leoncini PP, Locatelli F, et al.
Cell Death Differ 2019 Aug 21

Gedunin Degrades Aggregates of Mutant Huntingtin Protein and Intranuclear Inclusions via the Proteasomal Pathway in Neurons and Fibroblasts from Patients with Huntington's Disease.
Yang W, Xie J, Qiang Q, Li L, Lin X, et al.
Neurosci Bull 2019 Aug 20

Protopanaxadiol inhibits epithelial-mesenchymal transition of hepatocellular carcinoma by targeting STAT3 pathway.
Yang L, Zhang XY, Li K, Li AP, Yang WD, et al.
Cell Death Dis 2019 Aug 20

[Clinicopathological study of BCOR rearrangement in high grade endometrial stromal sarcoma].
Cheng YF, Bai QM, Bi R, Chang B, Huang D, et al.
Zhonghua Bing Li Xue Za Zhi 2019 Aug 8

Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β.
Talty A, Deegan S, Ljujic M, Mnich K, Naicker SD, et al.
Cell Death Dis 2019 Aug 16

Pembrolizumab in relapsed or refractory Hodgkin lymphoma: 2-year follow-up of KEYNOTE-087.
Chen R, Zinzani PL, Lee HJ, Armand P, Johnson NA, et al.
Blood 2019 Oct 3

Microglial-induced apoptosis is potentially responsible for hyperalgesia variations during CFA-induced inflammation.
Baniasadi M, Manaheji H, Maghsoudi N, Danyali S, Zakeri Z, et al.
Inflammopharmacology 2019 Aug 6

Tumor-treating fields induce autophagy by blocking the Akt2/miR29b axis in glioblastoma cells.
Kim EH, Jo Y, Sai S, Park MJ, Kim JY, et al.
Oncogene 2019 Sep

Maternal control of suspensor programmed cell death via gibberellin signaling.
Shi C, Luo P, Du YT, Chen H, Huang X, et al.
Nat Commun 2019 Aug 2

Mechanisms of doxorubicin-induced drug resistance and drug resistant tumour growth in a murine breast tumour model.
Christowitz C, Davis T, Isaacs A, van Niekerk G, Hattingh S, et al.
BMC Cancer 2019 Aug 1

ZBP1/DAI Drives RIPK3-Mediated Cell Death Induced by IFNs in the Absence of RIPK1.
Ingram JP, Thapa RJ, Fisher A, Tummers B, Zhang T, et al.
J Immunol 2019 Sep 1

Chloroplast-Localized Protoporphyrinogen IX Oxidase1 Is Involved in the Mitotic Cell Cycle in Arabidopsis.
Li J, Zhang F, Li Y, Yang W, Lin R, et al.
Plant Cell Physiol 2019 Nov 1

Oridonin enhances TRAIL-induced apoptosis through GALNT14-mediated DR5 glycosylation.
Jeon MY, Seo SU, Woo SM, Min KJ, Byun HS, et al.
Biochimie 2019 Oct

Rational application of the first-line chemotherapy and immune checkpoint inhibitors in advanced nonsmall cell lung cancer: A meta-analysis.
Cao R, Ma JT, Zhang SL, Sun L, Liu Y, et al.
Cancer Med 2019 Sep

Herbal formula Yangyinjiedu induces lung cancer cell apoptosis via activation of early growth response 1.
Yang W, Kang Y, Zhao Q, Bi L, Jiao L, et al.
J Cell Mol Med 2019 Sep

BOK promotes erythropoiesis in a mouse model of myelodysplastic syndrome.
Kang SH, Perales O, Michaud M, Katz SG
Ann Hematol 2019 Sep

RGD-containing elastin-like polypeptide improves islet transplantation outcomes in diabetic mice.
Lee KM, Kim JH, Choi ES, Kim E, Choi SK, et al.
Acta Biomater 2019 Aug

Staphylococcus aureus Orchestrates Type 2 Airway Diseases.
Teufelberger AR, Bröker BM, Krysko DV, Bachert C, Krysko O, et al.
Trends Mol Med 2019 Aug

Combined effect of alpha particles and cigarette smoke on human lung epithelial cells in vitro.
Lee US, Kim EH
Int J Radiat Biol 2019 Sep

The paracrine effects of fibroblasts on Doxorubicin-treated breast cancer cells.
Fourie C, Davis T, Kriel J, Engelbrecht AM
Exp Cell Res 2019 Aug 15

EMT is the major target for okadaic acid-suppressed the development of neural crest cells in chick embryo.
Jiao YH, Liu M, Wang G, Li HY, Liu JS, et al.
Ecotoxicol Environ Saf 2019 Sep 30

Apoptotic effect of Gyejibokryunghwan on uterine sarcoma cells (SK-UT-1B).
Park NC, Han SJ, Lee JW, Choi HJ, Kim EJ, et al.
Phytomedicine 2019 Aug

Matrix Metalloproteinase 11 Is a Potential Therapeutic Target in Lung Adenocarcinoma.
Yang H, Jiang P, Liu D, Wang HQ, Deng Q, et al.
Mol Ther Oncolytics 2019 Sep 27

NEAT1 promotes myocardial ischemia-reperfusion injury via activating the MAPK signaling pathway.
Du XJ, Wei J, Tian D, Yan C, Hu P, et al.
J Cell Physiol 2019 Aug

Protease/antiprotease network in allergy: The role of Staphylococcus aureus protease-like proteins.
Krysko O, Teufelberger A, Van Nevel S, Krysko DV, Bachert C, et al.
Allergy 2019 Nov

Cell cycle arrest in mitosis promotes interferon-induced necroptosis.
Frank T, Tuppi M, Hugle M, Dötsch V, van Wijk SJL, et al.
Cell Death Differ 2019 Oct

Author Correction: Caveolin-1 impairs PKA-DRP1-mediated remodelling of ER-mitochondria communication during the early phase of ER stress.
Bravo-Sagua R, Parra V, Ortiz-Sandoval C, Navarro-Marquez M, Rodríguez AE, et al.
Cell Death Differ 2019 Nov

Accurate elimination of superfluous attachment cells is critical for the construction of functional multicellular proprioceptors in Drosophila.
Avetisyan A, Salzberg A
Cell Death Differ 2019 Oct

Noncoding RNAs regulating cardiac muscle mass.
Wadley GD, Lamon S, Alexander SE, McMullen JR, Bernardo BC, et al.
J Appl Physiol (1985) 2019 Aug 1

Phosphoprotein patterns predict trametinib responsiveness and optimal trametinib sensitisation strategies in melanoma.
Rožanc J, Sakellaropoulos T, Antoranz A, Guttà C, Podder B, et al.
Cell Death Differ 2019 Aug