Member Publications

Comprehensive RNA-Seq Analysis of Potential Therapeutic Targets of Gan-Dou-Fu-Mu Decoction for Treatment of Wilson Disease Using a Toxic Milk Mouse Model.
Wei T, Hao W, Tang L, Wu H, Huang S, et al.
Front Pharmacol 2021

BNIP3 promotes HIF-1α-driven melanoma growth by curbing intracellular iron homeostasis.
Vara-Pérez M, Rossi M, Van den Haute C, Maes H, Sassano ML, et al.
EMBO J 2021 May 1

Molecular Mechanisms of Apoptosis Induction and Its Regulation by Fatty Acids in Pancreatic β-Cells.
Šrámek J, Němcová-Fürstová V, Kovář J
Int J Mol Sci 2021 Apr 20

Cyclin-Dependent Kinase Inhibitor BMI-1026 Induces Apoptosis by Downregulating Mcl-1 (L) and c-FLIP (L) and Inactivating p-Akt in Human Renal Carcinoma Cells.
Kim DE, Lee J, Park JW, Kang H, Nam YR, et al.
Int J Mol Sci 2021 Apr 20

Clusterin Deficiency Exacerbates Hyperoxia-Induced Acute Lung Injury.
Hong JY, Kim MN, Kim EG, Lee JW, Kim HR, et al.
Cells 2021 Apr 19

Mechanistic connections between mitochondrial biology and regulated cell death.
Chipuk JE, Mohammed JN, Gelles JD, Chen Y
Dev Cell 2021 May 3

DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells.
Tarayrah-Ibraheim L, Maurice EC, Hadary G, Ben-Hur S, Kolpakova A, et al.
Nat Commun 2021 Apr 16

FCN3 functions as a tumor suppressor of lung adenocarcinoma through induction of endoplasmic reticulum stress.
Jang H, Jun Y, Kim S, Kim E, Jung Y, et al.
Cell Death Dis 2021 Apr 15

Endothelial cell autophagy in homeostasis and cancer.
Verhoeven J, Baelen J, Agrawal M, Agostinis P
FEBS Lett 2021 Apr 9

Longitudinal changes in skeletal muscle mass in patients with advanced squamous cell lung cancer.
Lee J, Kim EY, Kim E, Kim KG, Kim YJ, et al.
Thorac Cancer 2021 Apr 7

ADCK1 activates the β-catenin/TCF signaling pathway to promote the growth and migration of colon cancer cells.
Ji Y, Liu Y, Sun C, Yu L, Wang Z, et al.
Cell Death Dis 2021 Apr 6

A Commonly Used Biocide 2-N-octyl-4-isothiazolin-3-oneInduces Blood-Brain Barrier Dysfunction via Cellular Thiol Modification and Mitochondrial Damage.
Kim D, Kim EH, Choi S, Lim KM, Tie L, et al.
Int J Mol Sci 2021 Mar 4

Case of slowly progressive type 1 diabetes mellitus with drastically reduced insulin secretory capacity after immune checkpoint inhibitor treatment for advanced renal cell carcinoma.
Yamaguchi H, Miyoshi Y, Uehara Y, Fujii K, Nagata S, et al.
Diabetol Int 2021 Apr

Novel porphyrazine-based photodynamic anti-cancer therapy induces immunogenic cell death.
Turubanova VD, Mishchenko TA, Balalaeva IV, Efimova I, Peskova NN, et al.
Sci Rep 2021 Mar 30

A review on the role of gut microbiota in immune checkpoint blockade therapy for cancer.
Kim E, Ahn H, Park H
Mamm Genome 2021 Mar 30

TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy.
Wu W, Wang X, Sun Y, Berleth N, Deitersen J, et al.
Autophagy 2021 Mar 28

MiR-628-5p Inhibits Cervical Carcinoma Proliferation and Promotes Apoptosis by Targeting VEGF.
Wu X, Lei J, Zhou B, Sun Q, Gao Y, et al.
Am J Med Sci 2021 Apr

MicroRNA-32-5p inhibits epithelial-mesenchymal transition and metastasis in lung adenocarcinoma by targeting SMAD family 3.
Zhang JX, Yang W, Wu JZ, Zhou C, Liu S, et al.
J Cancer 2021

The oncogene Mct-1 promotes progression of hepatocellular carcinoma via enhancement of Yap-mediated cell proliferation.
Yang W, Ni Y, Yang S, Ji Y, Yang X, et al.
Cell Death Discov 2021 Mar 22

hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.
Wan X, Zhu L, Zhao L, Peng L, Xiong J, et al.
Cell Death Dis 2021 Mar 19

Dysregulation of miR-23b-5p promotes cell proliferation via targeting FOXM1 in hepatocellular carcinoma.
Yang X, Yang S, Song J, Yang W, Ji Y, et al.
Cell Death Discov 2021 Mar 15

Perspectives on Organelle Interaction, Protein Dysregulation, and Cancer Disease.
Díaz P, Sandoval-Bórquez A, Bravo-Sagua R, Quest AFG, Lavandero S, et al.
Front Cell Dev Biol 2021

The Hippo Pathway Effector YAP Promotes Ferroptosis via the E3 Ligase SKP2.
Yang WH, Lin CC, Wu J, Chao PY, Chen K, et al.
Mol Cancer Res 2021 Mar 11

Picornavirus 3C - a protease ensuring virus replication and subverting host responses.
Yi J, Peng J, Yang W, Zhu G, Ren J, et al.
J Cell Sci 2021 Mar 10

Cellular senescence: Silent operator and therapeutic target in cancer.
Ramu D, Shan TW, Hirpara JL, Pervaiz S
IUBMB Life 2021 Mar

PD-L1⁺ neutrophils contribute to injury-induced infection susceptibility.
Thanabalasuriar A, Chiang AJ, Morehouse C, Camara M, Hawkins S, et al.
Sci Adv 2021 Mar

Aromadendrin Protects Neuronal Cells from Methamphetamine-Induced Neurotoxicity by Regulating Endoplasmic Reticulum Stress and PI3K/Akt/mTOR Signaling Pathway.
Lee HS, Kim EN, Jeong GS
Int J Mol Sci 2021 Feb 25

Apoptotic Cells induce Proliferation of Peritoneal Macrophages.
Knuth AK, Huard A, Naeem Z, Rappl P, Bauer R, et al.
Int J Mol Sci 2021 Feb 24

The CDT of Helicobacter hepaticus induces pro-survival autophagy and nucleoplasmic reticulum formation concentrating the RNA binding proteins UNR/CSDE1 and P62/SQSTM1.
He W, Azzi-Martin L, Velasco V, Lehours P, Dubus P, et al.
PLoS Pathog 2021 Mar

Assessment of Atg7 and LC3II/LC3, as The Markers of Autophagy, in Sperm of Infertile Men with Globozoospermia: A Case-Control Study.
Foroozan-Boroojeni S, Tavalaee M, Zakeri Z, Lockshin RA, Nasr-Esfahani MH, et al.
Cell J 2021 Apr

The onco-immunological implications of Fusobacterium nucleatum in breast cancer.
Van der Merwe M, Van Niekerk G, Botha A, Engelbrecht AM
Immunol Lett 2021 Apr

YAP/TFEB pathway promotes autophagic cell death and hypertrophic cardiomyopathy in lysosomal storage diseases.
Rabinovich-Nikitin I, Kirshenbaum LA
J Clin Invest 2021 Mar 1

Noopept; a nootropic dipeptide, modulates persistent inflammation by effecting spinal microglia dependent Brain Derived Neurotropic Factor (BDNF) and pro-BDNF expression throughout apoptotic process.
Taghizadeh M, Maghsoudi N, Manaheji H, Akparov V, Baniasadi M, et al.
Heliyon 2021 Feb

Ferroptosis and Photodynamic Therapy Synergism: Enhancing Anticancer Treatment.
Mishchenko TA, Balalaeva IV, Vedunova MV, Krysko DV
Trends Cancer 2021 Feb 24

Collagen Type X Alpha 1 (COL10A1) Contributes to Cell Proliferation, Migration, and Invasion by Targeting Prolyl 4-Hydroxylase Beta Polypeptide (P4HB) in Breast Cancer.
Yang W, Wu X, Zhou F
Med Sci Monit 2021 Feb 27

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹.
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, et al.
Autophagy 2021 Jan

p53 induces ARTS to promote mitochondrial apoptosis.
Hao Q, Chen J, Liao J, Huang Y, Gan Y, et al.
Cell Death Dis 2021 Feb 24

Hydrogen gas inhalation alleviates myocardial ischemia-reperfusion injury by the inhibition of oxidative stress and NLRP3-mediated pyroptosis in rats.
Nie C, Ding X, A R, Zheng M, Li Z, et al.
Life Sci 2021 May 1

Zinc transporter ZIP7 is a novel determinant of ferroptosis.
Chen PH, Wu J, Xu Y, Ding CC, Mestre AA, et al.
Cell Death Dis 2021 Feb 19

Pretest Symptom Duration and Cycle Threshold Values for Severe Acute Respiratory Syndrome Coronavirus 2 Reverse-Transcription Polymerase Chain Reaction Predict Coronavirus Disease 2019 Mortality.
Miller EH, Zucker J, Castor D, Annavajhala MK, Sepulveda JL, et al.
Open Forum Infect Dis 2021 Feb

Selective killing of cancer cells harboring mutant RAS by concomitant inhibition of NADPH oxidase and glutathione biosynthesis.
Liu M, Wang D, Luo Y, Hu L, Bi Y, et al.
Cell Death Dis 2021 Feb 16

Systemic Immunomodulatory Effects of Combinatorial Treatment of Thalidomide and Dexamethasone on T Cells and Other Immune Cells.
Kim EJ, Kim JY, Choi HY, Lee H, Lee J, et al.
Yonsei Med J 2021 Feb

Immunostimulant hydrogel for the inhibition of malignant glioma relapse post-resection.
Zhang J, Chen C, Li A, Jing W, Sun P, et al.
Nat Nanotechnol 2021 Feb 1

Tomato SlPUB24 enhances resistance to Xanthomonas euvesicatoria pv. perforans race T3.
Liu X, Meng G, Wang M, Qian Z, Zhang Y, et al.
Hortic Res 2021 Feb 1

Oxidized phosphatidylcholines trigger ferroptosis in cardiomyocytes during ischemia-reperfusion injury.
Stamenkovic A, O'Hara KA, Nelson DC, Maddaford TG, Edel AL, et al.
Am J Physiol Heart Circ Physiol 2021 Mar 1

Impact of different patterns of metastasis in non-small-cell lung cancer patients.
da Silva LM, da Silva GT, Bergmann A, Costa GJ, Zamboni MM, et al.
Future Oncol 2021 Mar

Cell-cycle risk score more accurately determines the risk for metastases and death in prostatectomy patients compared with clinical features alone.
Swanson GP, Lenz L, Stone S, Cohen T
Prostate 2021 Mar

NINJ1 mediates plasma membrane rupture during lytic cell death.
Kayagaki N, Kornfeld OS, Lee BL, Stowe IB, O'Rourke K, et al.
Nature 2021 Mar

Modes of Regulated Cell Death in Cancer.
Koren E, Fuchs Y
Cancer Discov 2021 Feb

Activation mechanisms of inflammasomes by bacterial toxins.
Jing W, Lo Pilato J, Kay C, Man SM
Cell Microbiol 2021 Apr

Acute chest syndrome in pediatric sickle cell disease: Associations with racial composition and neighborhood deprivation.
Alishlash AS, Rutland SB, Friedman AJ, Hampton JI, Nourani A, et al.
Pediatr Blood Cancer 2021 Apr

USP22 controls necroptosis by regulating receptor-interacting protein kinase 3 ubiquitination.
Roedig J, Kowald L, Juretschke T, Karlowitz R, Ahangarian Abhari B, et al.
EMBO Rep 2021 Feb 3

Knockdown of long non‑coding RNA ANRIL inhibits the proliferation and promotes the apoptosis of Burkitt lymphoma cells through the TGF‑β1 signaling pathway.
Mao S, Jin J, Li Z, Yang W
Mol Med Rep 2021 Feb

Alternate PCR assays for screening of JH1 mutation associated with embryonic death in Jersey cattle.
Kumar A, Gupta ID, Mohan G, M R V, D RK, et al.
Mol Cell Probes 2021 Feb

Compound XiongShao Capsule ameliorates streptozotocin-induced diabetic peripheral neuropathy in rats via inhibiting apoptosis, oxidative - nitrosative stress and advanced glycation end products.
Yu MX, Lei B, Song X, Huang YM, Ma XQ, et al.
J Ethnopharmacol 2021 Mar 25

Antioxidant functions of DHHC3 suppress anti-cancer drug activities.
Sharma C, Yang W, Steen H, Freeman MR, Hemler ME, et al.
Cell Mol Life Sci 2021 Mar

The conserved microRNA miR-210 regulates lipid metabolism and photoreceptor maintenance in the Drosophila retina.
Lyu J, Chen Y, Yang W, Guo T, Xu X, et al.
Cell Death Differ 2021 Feb

Non-lethal message from the Holy Land: The first international conference on nonapoptotic roles of apoptotic proteins.
Arama E, Baena-Lopez LA, Fearnhead HO
FEBS J 2021 Apr

Correction: Global deletion of optineurin results in altered type I IFN signaling and abnormal bone remodeling in a model of Paget's disease.
Wong SW, Huang BW, Hu X, Kim EH, Kolb JP, et al.
Cell Death Differ 2021 Feb

Quantitative single-molecule imaging of TNFR1 reveals zafirlukast as antagonist of TNFR1 clustering and TNFα-induced NF-ĸB signaling.
Weinelt N, Karathanasis C, Smith S, Medler J, Malkusch S, et al.
J Leukoc Biol 2021 Feb

Conditioned media from blue light-emitting diode-exposed fibroblasts have an anti-inflammatory effect in vitro.
Oh PS, Kim EM, Lim S, Sohn MH, Jeong HJ, et al.
Lasers Med Sci 2021 Feb

MiR-647 promotes cisplatin-induced cell apoptosis via downregulating IGF2 in non-small cell lung cancer.
Jiang W, Zhao X, Yang W
Minerva Med 2021 Apr