Member Publications

Electrochemical degradation and saponification of porcine adipose tissue.
Pham TT, Stokolosa AM, Borden PA, Hansen KD, Hong EM, et al.
Sci Rep 2020 Nov 27

Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism.
Chong SJF, Iskandar K, Lai JXH, Qu J, Raman D, et al.
Nucleic Acids Res 2020 Nov 27

ATP13A2-mediated endo-lysosomal polyamine export counters mitochondrial oxidative stress.
Vrijsen S, Besora-Casals L, van Veen S, Zielich J, Van den Haute C, et al.
Proc Natl Acad Sci U S A 2020 Nov 23

Induction of Lysosomal Membrane Permeabilization Is a Major Event of FTY720-Mediated Non-Apoptotic Cell Death in Human Glioma Cells.
Min KJ, Kwon TK
Cancers (Basel) 2020 Nov 16

Vaccination with early ferroptotic cancer cells induces efficient antitumor immunity.
Efimova I, Catanzaro E, Van der Meeren L, Turubanova VD, Hammad H, et al.
J Immunother Cancer 2020 Nov

Amino Acid Starvation Sensitizes Resistant Breast Cancer to Doxorubicin-Induced Cell Death.
Thomas M, Davis T, Nell T, Sishi B, Engelbrecht AM, et al.
Front Cell Dev Biol 2020

Natural Bioactive Compounds as Emerging Therapeutic Molecules against Breast Cancer: Emphasis on the Role of Phytoestrogens.
M AS, P AK, Narayanankutty A
Curr Drug Targets 2020 Nov 9

Sorafenib increases tumor treating fields-induced cell death in glioblastoma by inhibiting STAT3.
Kim JY, Jo Y, Oh HK, Kim EH
Am J Cancer Res 2020

Rod Photoreceptor Neuroprotection in Dark-Reared Pde6brd10 Mice.
Berkowitz BA, Podolsky RH, Childers KL, Roche SL, Cotter TG, et al.
Invest Ophthalmol Vis Sci 2020 Nov 2

Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-9.
Noori AR, Tashakor A, Nikkhah M, Eriksson LA, Hosseinkhani S, et al.
Biochimie 2020 Oct 24

Soluble PD-L1 improved direct ARDS by reducing monocyte-derived macrophages.
Xu J, Wang J, Wang X, Tan R, Qi X, et al.
Cell Death Dis 2020 Oct 30

Correction: Overactivated sonic hedgehog signaling aggravates intrauterine adhesion via inhibiting autophagy in endometrial stromal cells.
Wei C, Pan Y, Zhang Y, Dai Y, Jiang L, et al.
Cell Death Dis 2020 Oct 30

Anti-leukemic effect of CDK9 inhibition in T-cell prolymphocytic leukemia.
Johansson P, Dierichs L, Klein-Hitpass L, Bergmann AK, Möllmann M, et al.
Ther Adv Hematol 2020

Low-Dose Total Skin Electron Beam Therapy as Part of a Multimodality Regimen for Treatment of Sézary Syndrome: Clinical, Immunologic, and Molecular Analysis.
Durgin JS, Jariwala NN, Wysocka M, Zhang KK, Maity A, et al.
JAMA Dermatol 2020 Oct 28

ATF4 links ER stress with reticulophagy in glioblastoma cells.
Zielke S, Kardo S, Zein L, Mari M, Covarrubias-Pinto A, et al.
Autophagy 2020 Oct 28

Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells.
Dastghaib S, Shojaei S, Mostafavi-Pour Z, Sharma P, Patterson JB, et al.
Cells 2020 Oct 22

Conjugation of biphenyl groups with poly(ethylene glycol) to enhance inhibitory effects on the PD-1/PD-L1 immune checkpoint interaction.
Kim EH, Ning B, Kawamoto M, Miyatake H, Kobatake E, et al.
J Mater Chem B 2020 Nov 18

BCL11B suppresses tumor progression and stem cell traits in hepatocellular carcinoma by restoring p53 signaling activity.
Yang WJ, Sun YF, Jin AL, Lv LH, Zhu J, et al.
Cell Death Dis 2020 Oct 22

Correction: Gut microbiota patterns associated with somatostatin in patients undergoing pancreaticoduodenectomy: a prospective study.
Li GQ, Zhang T, Yang WG, Zhong HL, Xiao P, et al.
Cell Death Discov 2020

Gut microbiota patterns associated with somatostatin in patients undergoing pancreaticoduodenectomy: a prospective study.
Li GQ, Zhang T, Yang WG, Zhong HL, Xiao P, et al.
Cell Death Discov 2020

Novel Ablation Therapy Using Endoscopic Irreversible Electroporation in the Bile Duct: A Pilot Animal Study.
Lee KW, Lee JM, Choi HS, Kim ES, Keum B, et al.
Clin Endosc 2020 Oct 20

Mouse Strain-Dependent Difference Toward the Staphylococcus aureus Allergen Serine Protease-Like Protein D Reveals a Novel Regulator of IL-33.
Teufelberger AR, Van Nevel S, Hulpiau P, Nordengrün M, Savvides SN, et al.
Front Immunol 2020

Predicating the Effector Proteins Secreted by Puccinia triticina Through Transcriptomic Analysis and Multiple Prediction Approaches.
Zhang Y, Wei J, Qi Y, Li J, Amin R, et al.
Front Microbiol 2020

A circular RNA from NFIX facilitates oxidative stress-induced H9c2 cells apoptosis.
Cui X, Dong Y, Li M, Wang X, Jiang M, et al.
In Vitro Cell Dev Biol Anim 2020 Oct

Structure-activity relationship studies of phenothiazine derivatives as a new class of ferroptosis inhibitors together with the therapeutic effect in an ischemic stroke model.
Yang W, Liu X, Song C, Ji S, Yang J, et al.
Eur J Med Chem 2020 Sep 18

How to reprogram human fibroblasts to neurons.
Xu Z, Su S, Zhou S, Yang W, Deng X, et al.
Cell Biosci 2020

Dipeptide YA is Responsible for the Positive Effect of Oyster Hydrolysates on Alcohol Metabolism in Single Ethanol Binge Rodent Models.
Siregar AS, Nyiramana MM, Kim EJ, Shin EJ, Woo MS, et al.
Mar Drugs 2020 Oct 11

Magnolol Enhances the Therapeutic Effects of TRAIL through DR5 Upregulation and Downregulation of c-FLIP and Mcl-1 Proteins in Cancer Cells.
Woo SM, Min KJ, Kwon TK
Molecules 2020 Oct 8

Abstract 466: Vascular Claudin-11 Plays a Protective Role for Human Atherosclerosis Progression.
Kim EH, Jung MH, Park MS, Choi KH, Lee SJ, et al.
Circ Res 2020 Jul 31

Targeted inhibition of c-MET by podophyllotoxin promotes caspase-dependent apoptosis and suppresses cell growth in gefitinib-resistant non-small cell lung cancer cells.
Oh HN, Kwak AW, Lee MH, Kim E, Yoon G, et al.
Phytomedicine 2021 Jan

MiR-135-5p inhibits TGF-β-induced epithelial-mesenchymal transition and metastasis by targeting SMAD3 in breast cancer.
Yang W, Feng W, Wu F, Gao Y, Sun Q, et al.
J Cancer 2020

Apoptotic stress induces Bax-dependent, caspase-independent redistribution of LINC complex nesprins.
Lindenboim L, Grozki D, Amsalem-Zafran AR, Peña-Blanco A, Gundersen GG, et al.
Cell Death Discov 2020

Hepatic inflammation after burn injury is associated with necroptotic cell death signaling.
Idrovo JP, Boe DM, Kaahui S, Yang WL, Kovacs EJ, et al.
J Trauma Acute Care Surg 2020 Oct

Targeted scavenging of extracellular ROS relieves suppressive immunogenic cell death.
Deng H, Yang W, Zhou Z, Tian R, Lin L, et al.
Nat Commun 2020 Oct 2

Cell Death in the Tumor Microenvironment: Implications for Cancer Immunotherapy.
Gadiyar V, Lahey KC, Calianese D, Devoe C, Mehta D, et al.
Cells 2020 Sep 29

Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion.
Seo HG, Kim HB, Yoon JY, Kweon TH, Park YS, et al.
Cell Death Dis 2020 Sep 29

Correction: Smac mimetic suppresses tunicamycin-induced apoptosis via resolution of ER stress.
Abhari BA, McCarthy N, Le Berre M, Kilcoyne M, Joshi L, et al.
Cell Death Dis 2020 Sep 25

Integration of innate immune signalling by caspase-8 cleavage of N4BP1.
Gitlin AD, Heger K, Schubert AF, Reja R, Yan D, et al.
Nature 2020 Nov

PIGU promotes hepatocellular carcinoma progression through activating NF-κB pathway and increasing immune escape.
Wei X, Yang W, Zhang F, Cheng F, Rao J, et al.
Life Sci 2020 Nov 1

Pneumocystis jirovecii pneumonia in diffuse large B-cell Lymphoma treated with R-CHOP.
Lee JY, Kang M, Suh KJ, Kim JW, Kim SH, et al.
Mycoses 2020 Sep 24

Sulforaphene Ameliorates Neuroinflammation and Hyperphosphorylated Tau Protein via Regulating the PI3K/Akt/GSK-3β Pathway in Experimental Models of Alzheimer's Disease.
Yang W, Liu Y, Xu QQ, Xian YF, Lin ZX, et al.
Oxid Med Cell Longev 2020

Bip inhibition in glioma stem cells promotes radiation-induced immunogenic cell death.
Yang W, Xiu Z, He Y, Huang W, Li Y, et al.
Cell Death Dis 2020 Sep 22

Interleukin-4-loaded hydrogel scaffold regulates macrophages polarization to promote bone mesenchymal stem cells osteogenic differentiation via TGF-β1/Smad pathway for repair of bone defect.
Zhang J, Shi H, Zhang N, Hu L, Jing W, et al.
Cell Prolif 2020 Oct

Quietness of circular RNA circ_0054633 alleviates the inflammation and proliferation in lipopolysaccharides-induced acute lung injury model through NF-κB signaling pathway.
Yang CL, Yang WK, He ZH, Guo JH, Yang XG, et al.
Gene 2021 Jan 15

PIG-1 MELK-dependent phosphorylation of nonmuscle myosin II promotes apoptosis through CES-1 Snail partitioning.
Wei H, Lambie EJ, Osório DS, Carvalho AX, Conradt B, et al.
PLoS Genet 2020 Sep

Resveratrol inhibits hypertrophic scars formation by activating autophagy via the miR-4654/Rheb axis.
Pang K, Li B, Tang Z, Yang W, Hao L, et al.
Mol Med Rep 2020 Oct

Diversifying the platinum-based chemotherapy toolkit for immunogenic cancer cell death.
Garg AD, Agostinis P
Oncotarget 2020 Sep 8

Overactivated sonic hedgehog signaling aggravates intrauterine adhesion via inhibiting autophagy in endometrial stromal cells.
Wei C, Pan Y, Zhang Y, Dai Y, Jiang L, et al.
Cell Death Dis 2020 Sep 15

Self-luminescent photodynamic therapy using breast cancer targeted proteins.
Kim EH, Park S, Kim YK, Moon M, Park J, et al.
Sci Adv 2020 Sep

The conserved microRNA miR-210 regulates lipid metabolism and photoreceptor maintenance in the Drosophila retina.
Lyu J, Chen Y, Yang W, Guo T, Xu X, et al.
Cell Death Differ 2020 Sep 10

Potential Role of PDGFRβ-Associated THBS4 in Colorectal Cancer Development.
Kim MS, Choi HS, Wu M, Myung J, Kim EJ, et al.
Cancers (Basel) 2020 Sep 6

Inhibition of NF-κB is required for oleanolic acid to downregulate PD-L1 by promoting DNA demethylation in gastric cancer cells.
Lu X, Li Y, Yang W, Tao M, Dai Y, et al.
J Biochem Mol Toxicol 2020 Sep 7

Non-lethal message from the Holy Land: The first international conference on nonapoptotic roles of apoptotic proteins.
Arama E, Baena-Lopez LA, Fearnhead HO
FEBS J 2020 Sep 3

Descriptive Analysis of Histiocytic and Dendritic Cell Neoplasms: A Single-Institution Experience.
Kim HM, Yang WI, Lyu CJ, Hahn SM, Yoon SO, et al.
Yonsei Med J 2020 Sep

Pyridoxine induces monocyte-macrophages death as specific treatment of acute myeloid leukemia.
Yang W, Liu S, Li Y, Wang Y, Deng Y, et al.
Cancer Lett 2020 Nov 1

FTY720 induces ferroptosis and autophagy via PP2A/AMPK pathway in multiple myeloma cells.
Zhong Y, Tian F, Ma H, Wang H, Yang W, et al.
Life Sci 2020 Nov 1

Pathway-Guided Deep Neural Network toward Interpretable and Predictive Modeling of Drug Sensitivity.
Deng L, Cai Y, Zhang W, Yang W, Gao B, et al.
J Chem Inf Model 2020 Oct 26

Necroptosis restricts influenza A virus as a stand-alone cell death mechanism.
Shubina M, Tummers B, Boyd DF, Zhang T, Yin C, et al.
J Exp Med 2020 Nov 2

Synthesis and anti-cancer activity of bis-amino-phosphine ligand and its ruthenium(II) complexes.
Engelbrecht Z, Roberts KE, Hussan A, Amenuvor G, Cronjé MJ, et al.
Bioorg Med Chem Lett 2020 Oct 15

Preoperative soluble VCAM-1 contributes to predict late mortality after coronary artery surgery.
Corbalan R, Garcia M, Garrido-Olivares L, Garcia L, Perez G, et al.
Clin Cardiol 2020 Nov

Inhibition of kinesin motor protein KIFC1 by AZ82 induces multipolar mitosis and apoptosis in prostate cancer cell.
Parvin A, Hao SL, Tan FQ, Yang WX
Gene 2020 Nov 15

Identifying germline APOBEC3B deletion and immune phenotype in Korean patients with operable breast cancer.
Kim SH, Ahn S, Suh KJ, Kim YJ, Park SY, et al.
Breast Cancer Res Treat 2020 Oct

Targeting topoisomerase II with trypthantrin derivatives: Discovery of 7-((2-(dimethylamino)ethyl)amino)indolo[2,1-b]quinazoline-6,12-dione as an antiproliferative agent and to treat cancer.
Catanzaro E, Betari N, Arencibia JM, Montanari S, Sissi C, et al.
Eur J Med Chem 2020 Sep 15

Comparative proteomic analysis uncovers potential biomarkers involved in the anticancer effect of Scutellarein in human gastric cancer cells.
Saralamma VVG, Vetrivel P, Lee HJ, Kim SM, Ha SE, et al.
Oncol Rep 2020 Sep

Mortalin peptides exert antitumor activities and act as adjuvants to antibody-mediated complement-dependent cytotoxicity.
Jubran R, Saar-Ray M, Wawruszak A, Ziporen L, Donin N, et al.
Int J Oncol 2020 Oct

Correction: JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction.
Simula L, Corrado M, Accordi B, Di Rita A, Nazio F, et al.
Cell Death Differ 2020 Nov

Rationally designed redirection of natural killer cells anchoring a cytotoxic ligand for pancreatic cancer treatment.
Lee YE, Ju A, Choi HW, Kim JC, Kim EE, et al.
J Control Release 2020 Oct 10

N-Adamantyl-4-methylthiazol-2-amine suppresses glutamate-induced autophagic cell death via PI3K/Akt/mTOR signaling pathways in cortical neurons.
Yang SJ, Han AR, Choi HR, Hwang K, Kim EA, et al.
BMB Rep 2020 Nov

Inhibiting the inhibitors: Targeting anti-apoptotic proteins in cancer and therapy resistance.
Shahar N, Larisch S
Drug Resist Updat 2020 Sep

Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes.
Lampl S, Janas MK, Donakonda S, Brugger M, Lohr K, et al.
J Hepatol 2020 Dec

Risk of bacteremia in patients with cutaneous T-cell lymphoma (CTCL).
Allen PB, Switchenko J, Ayers A, Kim E, Lechowicz MJ, et al.
Leuk Lymphoma 2020 Nov

Open-label, Phase I Study of Nivolumab Combined with nab-Paclitaxel Plus Gemcitabine in Advanced Pancreatic Cancer.
Wainberg ZA, Hochster HS, Kim EJ, George B, Kaylan A, et al.
Clin Cancer Res 2020 Sep 15

Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway.
Liu Y, Wen D, Gao J, Xie B, Yu H, et al.
Brain Res Bull 2020 Sep

Chemosensitivity to HM90822, a novel synthetic IAP antagonist, is determined by p-AKT-inducible XIAP phosphorylation in human pancreatic cancer cells.
Hong SW, Shin JS, Moon JH, Jung SA, Koh DI, et al.
Invest New Drugs 2020 Dec

The proteasome activator REGγ accelerates cardiac hypertrophy by declining PP2Acα-SOD2 pathway.
Xie Y, Gao Y, Gao R, Yang W, Dong Z, et al.
Cell Death Differ 2020 Oct

CD9 induces cellular senescence and aggravates atherosclerotic plaque formation.
Cho JH, Kim EC, Son Y, Lee DW, Park YS, et al.
Cell Death Differ 2020 Sep

JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction.
Simula L, Corrado M, Accordi B, Di Rita A, Nazio F, et al.
Cell Death Differ 2020 Oct

Global injury morbidity and mortality from 1990 to 2017: results from the Global Burden of Disease Study 2017.
James SL, Castle CD, Dingels ZV, Fox JT, Hamilton EB, et al.
Inj Prev 2020 Oct

Proteasome inhibitors and Smac mimetics cooperate to induce cell death in diffuse large B-cell lymphoma by stabilizing NOXA and triggering mitochondrial apoptosis.
Dietz A, Dalda N, Zielke S, Dittmann J, van Wijk SJL, et al.
Int J Cancer 2020 Sep 1

Angiotensin-(1-9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway.
Sotomayor-Flores C, Rivera-Mejías P, Vásquez-Trincado C, López-Crisosto C, Morales PE, et al.
Cell Death Differ 2020 Sep