Member Publications

Arylquin 1, a potent Par-4 secretagogue, induces lysosomal membrane permeabilization-mediated non-apoptotic cell death in cancer cells.
Min KJ, Shahriyar SA, Kwon TK
Toxicol Res 2020 Apr

Risk factors for early mortality in patients with primary central nervous system lymphoma: A large-cohort retrospective study.
Zhou X, Niu X, Li J, Zhang S, Yang W, et al.
World Neurosurg 2020 Apr 3

The clearance of dead cells by efferocytosis.
Boada-Romero E, Martinez J, Heckmann BL, Green DR
Nat Rev Mol Cell Biol 2020 Apr 6

mPGES-1/PGE2 promotes the growth of T-ALL cells in vitro and in vivo by regulating the expression of MTDH via the EP3/cAMP/PKA/CREB pathway.
Li Y, Chen J, Yang W, Liu H, Wang J, et al.
Cell Death Dis 2020 Apr 6

Characterization of the relationship between FLI1 and immune infiltrate level in tumour immune microenvironment for breast cancer.
Wang S, Wang Y, Yu C, Cao Y, Yu Y, et al.
J Cell Mol Med 2020 Apr 5

Correction to: Induction of immunogenic cell death in radiation-resistant breast cancer stem cells by repurposing anti-alcoholism drug disulfiram.
Sun T, Yang W, Toprani SM, Guo W, He L, et al.
Cell Commun Signal 2020 Apr 2

Disulfiram/cytarabine eradicates a subset of acute myeloid leukemia stem cells with high aldehyde dehydrogenase expression.
Yang W, Xie J, Hou R, Chen X, Xu Z, et al.
Leuk Res 2020 Mar 19

Dihydroartemisinin-Loaded Magnetic Nanoparticles for Enhanced Chemodynamic Therapy.
Guo S, Yao X, Jiang Q, Wang K, Zhang Y, et al.
Front Pharmacol 2020

UPF1 Participates in the Progression of Endometrial Cancer by Inhibiting the Expression of lncRNA PVT1.
Xing TR, Chen P, Wu JM, Gao LL, Yang W, et al.
Onco Targets Ther 2020

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death.
Galluzzi L, Vitale I, Warren S, Adjemian S, Agostinis P, et al.
J Immunother Cancer 2020 Mar

Frontiers of ctDNA, targeted therapies, and immunotherapy in non-small-cell lung cancer.
Zhu C, Zhuang W, Chen L, Yang W, Ou WB, et al.
Transl Lung Cancer Res 2020 Feb

Sea Hare Hydrolysate-Induced Reduction of Human Non-Small Cell Lung Cancer Cell Growth through Regulation of Macrophage Polarization and Non-Apoptotic Regulated Cell Death Pathways.
Nyiramana MM, Cho SB, Kim EJ, Kim MJ, Ryu JH, et al.
Cancers (Basel) 2020 Mar 19

Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis.
Zhang T, Yin C, Boyd DF, Quarato G, Ingram JP, et al.
Cell 2020 Mar 19

Mammalian Sterile 20-like Kinase (MST) 1/2: Crucial Players in Nervous and Immune System and Neurological Disorders.
Qi Y, Sun D, Yang W, Xu B, Lv D, et al.
J Mol Biol 2020 Mar 17

Cx43 channels and signaling via IP₃/Ca²⁺, ATP, and ROS/NO propagate radiation-induced DNA damage to non-irradiated brain microvascular endothelial cells.
Hoorelbeke D, Decrock E, De Smet M, De Bock M, Descamps B, et al.
Cell Death Dis 2020 Mar 18

Dual Targeting of the p38 MAPK-HO-1 Axis and cIAP1/XIAP by Demethoxycurcumin Triggers Caspase-Mediated Apoptotic Cell Death in Oral Squamous Cell Carcinoma Cells.
Chien MH, Yang WE, Yang YC, Ku CC, Lee WJ, et al.
Cancers (Basel) 2020 Mar 16

Carbon-Ion Beam Irradiation Alone or in Combination with Zoledronic acid Effectively Kills Osteosarcoma Cells.
Kim EH, Kim MS, Takahashi A, Suzuki M, Vares G, et al.
Cancers (Basel) 2020 Mar 16

A 3D Cell Death Assay to Quantitatively Determine Ferroptosis in Spheroids.
Demuynck R, Efimova I, Lin A, Declercq H, Krysko DV, et al.
Cells 2020 Mar 13

Targeting XIAP for Promoting Cancer Cell Death-The Story of ARTS and SMAC.
Abbas R, Larisch S
Cells 2020 Mar 9

Decoding cancer cell death-driven immune cell recruitment: An in vivo method for site-of-vaccination analyses.
Fang S, Agostinis P, Salven P, Garg AD
Methods Enzymol 2020

Proteasome inhibitors and Smac mimetics cooperate to induce cell death in diffuse large B-cell lymphoma by stabilizing NOXA and triggering mitochondrial apoptosis.
Dietz A, Dalda N, Zielke S, Dittmann J, van Wijk SJL, et al.
Int J Cancer 2020 Mar 13

Ionizing radiation regulates vascular endothelial growth factor-A transcription in cultured human vascular endothelial cells via the PERK/eIF2α/ATF4 pathway.
Kim EJ, Lee H, Lee YJ, Sonn JK, Lim YB, et al.
Int J Radiat Oncol Biol Phys 2020 Mar 10

Co-inhibition of BET proteins and PI3Kα triggers mitochondrial apoptosis in rhabdomyosarcoma cells.
Boedicker C, Hussong M, Grimm C, Dolgikh N, Meister MT, et al.
Oncogene 2020 Mar 11

Biology of phosphatidylserine (PS): basic physiology and implications in immunology, infectious disease, and cancer.
Calianese DC, Birge RB
Cell Commun Signal 2020 Mar 11

Engrailed 2 (EN2) acts as a glioma suppressor by inhibiting tumor proliferation/invasion and enhancing sensitivity to temozolomide.
Li T, Yang W, Li M, Zhang S, Zhou X, et al.
Cancer Cell Int 2020

Angiotensin-(1-9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway.
Sotomayor-Flores C, Rivera-Mejías P, Vásquez-Trincado C, López-Crisosto C, Morales PE, et al.
Cell Death Differ 2020 Mar 9

Full-Process Radiosensitization Based on Nanoscale Metal-Organic Frameworks.
Gong T, Li Y, Lv B, Wang H, Liu Y, et al.
ACS Nano 2020 Mar 24

Cell death through the ages: The ICDS 25th Anniversary Meeting.
Mohammed JN, Gelles JD, Rubio-Patiño C, Serasinghe MN, Trotta AP, et al.
FEBS J 2020 Mar 8

Janus kinase 2 inhibition by Licochalcone B suppresses esophageal squamous cell carcinoma growth.
Song M, Yoon G, Choi JS, Kim E, Liu X, et al.
Phytother Res 2020 Mar 6

Induction of immunogenic cell death in radiation-resistant breast cancer stem cells by repurposing anti-alcoholism drug disulfiram.
Sun T, Yang W, Toprani SM, Guo W, He L, et al.
Cell Commun Signal 2020 Mar 5

A competent bidrug loaded water soluble chitosan derivative for the effective inhibition of breast cancer.
E A K N, S B, Martin CA, J RR, A S, et al.
Sci Rep 2020 Mar 4

Lupenone Protects Neuroblastoma SH-SY5y Cells Against Methamphetamine-Induced Apoptotic Cell Death via PI3K/Akt/mTOR Signaling Pathway.
Lee HS, Kim EN, Jeong GS
Int J Mol Sci 2020 Feb 27

Memantine Displays Antimicrobial Activity by Enhancing <i>Escherichia coli</i> Pathogen-Induced Formation of Neutrophil Extracellular Traps.
Peng L, Li L, He XL, Yu JY, Zeng ZJ, et al.
Front Cell Infect Microbiol 2020

Identification of the Prognosis-Related lncRNAs and Genes in Gastric Cancer.
Su X, Zhang J, Yang W, Liu Y, Liu Y, et al.
Front Genet 2020

Low concentrations of methamphetamine can suppress inflammation in trophoblast JEG-3 cell line induced by nicotine.
H Z, A AR, K A
Bratisl Lek Listy 2020

A novel programmed cell death protein 4 negatively regulates CgIL17-5 expression in hemocytes of oyster Pacific oyster (Crassostrea gigas).
Yan Y, Wang W, Liu Z, Lv X, Li M, et al.
Fish Shellfish Immunol 2020 Apr

Classification of analytics, sensorics, and bioanalytics with polyelectrolyte multilayer capsules.
Van der Meeren L, Li J, Parakhonskiy BV, Krysko DV, Skirtach AG, et al.
Anal Bioanal Chem 2020 Feb 27

Lipid availability determines fate of skeletal progenitor cells via SOX9.
van Gastel N, Stegen S, Eelen G, Schoors S, Carlier A, et al.
Nature 2020 Mar

Altered distribution and enhanced osteoclastogenesis of mucosal-associated invariant T cells in gouty arthritis.
Cho YN, Jeong HS, Park KJ, Kim HS, Kim EH, et al.
Rheumatology (Oxford) 2020 Feb 22

Corrigendum to "Concurrent MEK and autophagy inhibition is required to restore cell death associated danger-signalling in Vemurafenib-resistant melanoma cells" [Biochem. Pharmacol. 93 (3) (2015) 290-304].
Martin S, Dudek-Perić AM, Maes H, Garg AD, Gabrysiak M, et al.
Biochem Pharmacol 2020 Feb 18

Midazolam and isoflurane combination reduces late brain damage in the paraoxon-induced status epilepticus rat model.
Swissa E, Bar-Klein G, Serlin Y, Weissberg I, Kamintsky L, et al.
Neurotoxicology 2020 Feb 18

Endoplasmic Reticulum Targeting to Amplify Immunogenic Cell Death for Cancer Immunotherapy.
Deng H, Zhou Z, Yang W, Lin LS, Wang S, et al.
Nano Lett 2020 Mar 11

CEPO (carbamylated erythropoietin)-Fc protects hippocampal cells in culture against beta amyloid-induced apoptosis: considering Akt/GSK-3β and ERK signaling pathways.
Hooshmandi E, Moosavi M, Katinger H, Sardab S, Ghasemi R, et al.
Mol Biol Rep 2020 Mar

Potential diagnostic value of PD-1 in peripheral blood mononuclear cells of postmenopausal osteoporosis patients.
Cai XP, Zhao Q, Guo ZD, Lin SJ, Chen ZX, et al.
J Clin Lab Anal 2020 Feb 17

Bifenthrin insecticide promotes oxidative stress and increases inflammatory mediators in human neuroblastoma cells through NF-kappaB pathway.
Gargouri B, Boukholda K, Kumar A, Benazzouz A, Fetoui H, et al.
Toxicol In Vitro 2020 Feb 13

The Biofunctional Effects of Mesima as a Radiosensitizer for Hepatocellular Carcinoma.
Jeong YK, Oh JY, Yoo JK, Lim SH, Kim EH, et al.
Int J Mol Sci 2020 Jan 29

Abnormal expression of miR-135b-5p in bone tissue of patients with osteoporosis and its role and mechanism in osteoporosis progression.
Chen B, Yang W, Zhao H, Liu K, Deng A, et al.
Exp Ther Med 2020 Feb

A trustworthy CpG nanoplatform for highly safe and efficient cancer photothermal combined immunotherapy.
Ming J, Zhang J, Shi Y, Yang W, Li J, et al.
Nanoscale 2020 Feb 14

ATP13A2 deficiency disrupts lysosomal polyamine export.
van Veen S, Martin S, Van den Haute C, Benoy V, Lyons J, et al.
Nature 2020 Feb

Loss of BIM in T cells results in BCL-2 family BH3-member compensation but incomplete cell death sensitivity normalization.
Ludwig LM, Roach LE, Katz SG, LaBelle JL
Apoptosis 2020 Jan 28

Hippo pathway effectors YAP/TAZ as novel determinants of ferroptosis.
Yang WH, Chi JT
Mol Cell Oncol 2020

Why not add some SPARKL to your life (and death)!?
Gelles JD, Chipuk JE
Mol Cell Oncol 2020

Predictive factors of death associated with infective endocarditis in adult patients with congenital heart disease.
Ly R, Compain F, Gaye B, Pontnau F, Bouchard M, et al.
Eur Heart J Acute Cardiovasc Care 2020 Jan 28

RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence.
Lin CC, Mabe NW, Lin YT, Yang WH, Tang X, et al.
Cell Death Differ 2020 Jan 27

Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28.
Müller I, Strozyk E, Schindler S, Beissert S, Oo HZ, et al.
Mol Cell 2020 Mar 5

Chidamide induces necroptosis via regulation of c‑FLIPL expression in Jurkat and HUT‑78 cells.
Chi Z, Gao H, Liu H, Wu B, Zhang B, et al.
Mol Med Rep 2020 Feb

STF-62247 and pimozide induce autophagy and autophagic cell death in mouse embryonic fibroblasts.
Kinzler MN, Zielke S, Kardo S, Meyer N, Kögel D, et al.
Sci Rep 2020 Jan 20

Superoxide induced inhibition of death receptor signaling is mediated via induced expression of apoptosis inhibitory protein cFLIP.
Hirpara JL, Subramaniam K, Bellot G, Qu J, Seah S, et al.
Redox Biol 2020 Feb

Tunable light and drug induced depletion of target proteins.
Deng W, Bates JA, Wei H, Bartoschek MD, Conradt B, et al.
Nat Commun 2020 Jan 16

Facile synthesis of polypyrrole-rhodamine B nanoparticles for self-monitored photothermal therapy of cancer cells.
Wang XH, Chen XQ, Peng HS, Wei XF, Wang XJ, et al.
J Mater Chem B 2020 Feb 7

Detection of Ferroptosis by BODIPY™ 581/591 C11.
Martinez AM, Kim A, Yang WS
Methods Mol Biol 2020

Single-molecule imaging reveals the oligomeric state of functional TNFα-induced plasma membrane TNFR1 clusters in cells.
Karathanasis C, Medler J, Fricke F, Smith S, Malkusch S, et al.
Sci Signal 2020 Jan 14

Deoxyribonuclease Reduces Tissue Injury and Improves Survival After Hemorrhagic Shock.
Cagliani J, Yang WL, Brenner M, Wang P
J Surg Res 2020 May

An RXLR effector PlAvh142 from Peronophythora litchii triggers plant cell death and contributes to virulence.
Situ J, Jiang L, Fan X, Yang W, Li W, et al.
Mol Plant Pathol 2020 Mar

Anti-masculinization induced by aromatase inhibitors in adult female zebrafish.
Chen L, Wang L, Cheng Q, Tu YX, Yang Z, et al.
BMC Genomics 2020 Jan 7

Correction: Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β.
Talty A, Deegan S, Ljujic M, Mnich K, Naicker SD, et al.
Cell Death Dis 2020 Jan 6

A novel IFNα-induced long noncoding RNA negatively regulates immunosuppression by interrupting H3K27 acetylation in head and neck squamous cell carcinoma.
Ma H, Chang H, Yang W, Lu Y, Hu J, et al.
Mol Cancer 2020 Jan 6

Misfolded proteins bind and activate death receptor 5 to trigger apoptosis during unresolved endoplasmic reticulum stress.
Lam M, Marsters SA, Ashkenazi A, Walter P
Elife 2020 Jan 6

Cathepsin K inhibition-induced mitochondrial ROS enhances sensitivity of cancer cells to anti-cancer drugs through USP27x-mediated Bim protein stabilization.
Seo SU, Woo SM, Kim MW, Lee HS, Kim SH, et al.
Redox Biol 2020 Feb

Autophagy, replication stress and DNA synthesis, an intricate relationship.
Cecconi F
Cell Death Differ 2020 Feb

Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection.
Aaes TL, Verschuere H, Kaczmarek A, Heyndrickx L, Wiernicki B, et al.
J Immunol 2020 Feb 15

Smart Nanovesicle-Mediated Immunogenic Cell Death through Tumor Microenvironment Modulation for Effective Photodynamic Immunotherapy.
Yang W, Zhang F, Deng H, Lin L, Wang S, et al.
ACS Nano 2020 Jan 28

Exceptional Response of Cryoablation Followed by Pembrolizumab in a Patient with Metastatic Cervical Carcinosarcoma with High Tumor Mutational Burden: A Case Report.
Zhu B, Liu Y, Li J, Diao L, Shao L, et al.
Oncologist 2020 Jan

Fiery Cell Death: Pyroptosis in the Central Nervous System.
McKenzie BA, Dixit VM, Power C
Trends Neurosci 2020 Jan

Hemistepsin A alleviates liver fibrosis by inducing apoptosis of activated hepatic stellate cells via inhibition of nuclear factor-κB and Akt.
Kim JK, Han NR, Park SM, Jegal KH, Jung JY, et al.
Food Chem Toxicol 2020 Jan

Infertility Caused by Inefficient Apoptotic Germ Cell Clearance in <i>Xkr8</i>-Deficient Male Mice.
Yamashita Y, Suzuki C, Uchiyama Y, Nagata S
Mol Cell Biol 2020 Jan 16

Nanocomposite packaging regulates extracellular ATP and programed cell death in edible mushroom (Flammulina velutipes).
Shi C, Wu Y, Fang D, Ma N, Mariga AM, et al.
Food Chem 2020 Mar 30

Molecular insights on cytochrome c and nucleotide regulation of apoptosome function and its implication in cancer.
Yadav N, Gogada R, O'Malley J, Gundampati RK, Jayanthi S, et al.
Biochim Biophys Acta Mol Cell Res 2020 Jan

A matter of life and death: Molecular, physiological, and environmental regulation of seed longevity.
Zhou W, Chen F, Luo X, Dai Y, Yang Y, et al.
Plant Cell Environ 2020 Feb

A TAZ-ANGPTL4-NOX2 Axis Regulates Ferroptotic Cell Death and Chemoresistance in Epithelial Ovarian Cancer.
Yang WH, Huang Z, Wu J, Ding CC, Murphy SK, et al.
Mol Cancer Res 2020 Jan

The requirement of SUMO2/3 for SENP2 mediated extraembryonic and embryonic development.
Yu HI, Hsu T, Maruyama EO, Paschen W, Yang W, et al.
Dev Dyn 2020 Feb

Effect of novel porphyrazine photosensitizers on normal and tumor brain cells.
Mishchenko TA, Turubanova VD, Mitroshina EV, Alzeibak R, Peskova NN, et al.
J Biophotonics 2020 Jan

Emerging role of mitophagy in cardiovascular physiology and pathology.
Morales PE, Arias-Durán C, Ávalos-Guajardo Y, Aedo G, Verdejo HE, et al.
Mol Aspects Med 2020 Feb

Rotenone and 3-bromopyruvate toxicity impacts electrical and structural cardiac remodeling in rats.
Zhan C, Liu G, Li J, Li G, Li T, et al.
Toxicol Lett 2020 Jan

LanCL1 promotes motor neuron survival and extends the lifespan of amyotrophic lateral sclerosis mice.
Tan H, Chen M, Pang D, Xia X, Du C, et al.
Cell Death Differ 2020 Apr

Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells.
Pataer A, Ozpolat B, Shao R, Cashman NR, Plotkin SS, et al.
Oncogene 2020 Jan

HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy.
Strappazzon F, Di Rita A, Peschiaroli A, Leoncini PP, Locatelli F, et al.
Cell Death Differ 2020 Apr

Microglial-induced apoptosis is potentially responsible for hyperalgesia variations during CFA-induced inflammation.
Baniasadi M, Manaheji H, Maghsoudi N, Danyali S, Zakeri Z, et al.
Inflammopharmacology 2020 Apr

Thioredoxin inhibitor PX-12 induces mitochondria-mediated apoptosis in acute lymphoblastic leukemia cells.
Ehrenfeld V, Fulda S
Biol Chem 2020 Feb 25

Kinome screen of ferroptosis reveals a novel role of ATM in regulating iron metabolism.
Chen PH, Wu J, Ding CC, Lin CC, Pan S, et al.
Cell Death Differ 2020 Mar

NLRP3-dependent pyroptosis is required for HIV-1 gp120-induced neuropathology.
He X, Yang W, Zeng Z, Wei Y, Gao J, et al.
Cell Mol Immunol 2020 Mar

Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits.
Jung S, Choe S, Woo H, Jeong H, An HK, et al.
Autophagy 2020 Mar

Targeting ferroptosis in rhabdomyosarcoma cells.
Dächert J, Ehrenfeld V, Habermann K, Dolgikh N, Fulda S, et al.
Int J Cancer 2020 Jan 15

Concomitant targeting of BCL2 with venetoclax and MAPK signaling with cobimetinib in acute myeloid leukemia models.
Han L, Zhang Q, Dail M, Shi C, Cavazos A, et al.
Haematologica 2020 Mar

Targeting monocyte-intrinsic enhancer reprogramming improves immunotherapy efficacy in hepatocellular carcinoma.
Liu M, Zhou J, Liu X, Feng Y, Yang W, et al.
Gut 2020 Feb