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This page offers access to some classical pages about apoptosis and articles explaining apoptosis in an accessible form.

Anyone who has access to a potentially classical paper (at least 25 years old) or another article worth posting, please Contact the Webmaster

Classic Publications

Glücksmann (1951) : Cell Deaths in Normal Vertebrate Ontogeny

Lockshin and Williams (1964, 1965) :

I. Programmed Cell Death-I. Cytology of Degeneration in the Intersegmental Muscles of the Pernyi Silkmoth

II. Programmed Cell Death—II. Endocrine Potentiation of the Breakdown of the Intersegmental Muscles of Silkmoths

III. Programmed Cell Death-III. Neural Control of the Breakdown of the Intersegmental Muscles of Silkmoths

IV. Programmed Cell Death-IV. The Influence of Drugs on the Breakdown of the Intersegmental Muscles of Silkmoths

V. Programmed Cell Death—V. Cytolic Enzymes in Relation to the Breakdown of the Intersegmental Muscles of Silkmoths

Sulston/Horvitz (1977) : Post-embryonic cell lineages of the nematode, Caenorhabditis elegans.

Wyllie/Kerr/Currie (1982) : Apoptosis: A Basic Biological Phenomenon with Wide-Ranging Implications in Tissue Kinetics

Yuan/Shaham/Ledoux/Ellis/Horvitz (1993): The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme.

History of the Field

Clarke & Clarke (1996) :  Nineteenth century research on naturally occuring cell death and related phenomena

Häcker & Vaux (1997) : A chronology of cell death

Lockshin & Zakeri (2001) :  Programmed cell death and apoptosis: origins of the theory

Kerr (2002) :  History of the events leading to the formulation of the apoptosis concept

Vaux (2002) : Apoptosis timeline

About Apoptosis

Ma Antonia Lizarbe Iracheta (2007) :

El suicido y la muerte celular (in the original Spanish)

Cell Suicide and Cell Death